96091-4

SARS-CoV-2 (COVID-19) RdRp gene [Presence] in Saliva (oral fluid) by NAA with probe detection

Active

Term Description

Qualitative detection of nucleic acids within the RdRp gene of SARS coronavirus 2 (SARS-CoV-2) in saliva specimens by nucleic acid amplification with probe-based detection. Testing is performed for the diagnosis of Coronavirus disease 2019 (COVID-19).
Source: Regenstrief LOINC

Part Descriptions

LP417598-2   SARS coronavirus 2 RdRp gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

Reference Information

Fully-Specified Name

Component

SARS coronavirus 2 RdRp gene

Property

PrThr

Time

Pt

System

Saliva

Scale

Ord

Method

Probe.amp.tar

Additional Names

Short Name

SARS-CoV-2 RdRp Sal Ql NAA+probe

Display Name

SARS-CoV-2 (COVID-19) RdRp gene NAA+probe Ql (Sal)

Consumer Name Alpha Get Info

SARS-CoV-2 (COVID-19) RdRp gene, Saliva

Example Answer List: LL5695-3

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.69

Last Updated

Version 2.69

Order vs. Observation

Both

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 2019 Novel Coronavirus
• 2019-nCoV
• 3 Self-Sustaining Sequence Replication
• 3SR SR
• Amplif
• Amplification
• Amplified
• Corona virus
• COVID19
• COVID-19
• DNA NUCLEIC ACID PROBE
• DNA probe
• ID
• II
• Infectious Disease
• InfectiousDisease
• LAT
• LCR
• Ligase chain reaction
• Ligation-activated transcription
• Microbiology
• NAA+probe
• NAAT
• NASBA
• Nucleic acid sequence based analysis
• Oral fluid
• Ordinal
• PCR
• Point in time
• Polymerase chain reaction
• PR
• Probe amp
• Probe with ampification
• Probe with target amplification
• QBR
• QL
• Qual
• Qualitative
• Random
• Sal
• SARS Coronavirus 1
• SARS-CoV
• SARS-CoV-1
• SARS-CoV-2
• SARS-CoV-2 RdRp
• Screen
• SDA
• Severe Acute Respiratory Syndrome
• Strand Displacement Amplification
• TMA
• Transcription mediated amplification
• Viral Pneumonias
• Wuhan coronavirus

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