96367-8
Pregabalin [Mass/volume] in Saliva (oral fluid) by Confirmatory method
Active
Part Descriptions
LP61621-6 Pregabalin
Pregabalin (brand name Lyrica) is an anticonvulsant gamma-aminobutyric acid analog drug used for neuropathic pain and as an adjunct therapy for partial seizures with or without secondary generalization in adults. It has also been found effective for generalized anxiety disorder. Studies have shown that pregabalin is effective at treating chronic pain in disorders such as fibromyalgia and spinal cord injury. It was designed as a more potent successor to gabapentin, and considered to have a low potential for abuse and limited dependence liability if misused. [PubChem:Pregabalin]
Source: Regenstrief LOINC
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Pregabalin
- Property
- MCnc
- Time
- Pt
- System
- Saliva
- Scale
- Qn
- Method
- Confirm
Additional Names
- Short Name
- Pregabalin Sal Cfm-mCnc
- Display Name
- Pregabalin Confirm (Sal) [Mass/Vol]
- Consumer Name Alpha Get Info
- Pregabalin, Saliva
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.69
- Last Updated
- Version 2.69
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG37665-3 | Pregabalin| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Pregabalina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Pregabalina: |
| et-EE | Estonian (Estonia) | Pregabaliin: Synonyms: Juhuslik Kvantitatiivne Sülg |
| fr-BE | French (Belgium) | Prégabaline: |
| fr-CA | French (Canada) | Prégabaline: |
| fr-FR | French (France) | Prégabaline: |
| it-IT | Italian (Italy) | Pregabalin: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | pregabaline: |
| ru-RU | Russian (Russian Federation) | Прегабалин: Synonyms: Количественный Массовая концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | Pregabalin: Synonyms: Teyid |
| zh-CN | Chinese (China) | 普瑞巴林: Synonyms: 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| ng/mL | Example UCUM Units |
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