Version 2.77

Part Description

LP21368-3   Sirolimus
Sirolimus, also known as rapamycin, is a macrolide compound that inhibits lymphocyte proliferation and is used as an immunosuppressant to prevent rejection in organ transplantation. It inhibits T-cell activation and proliferation by inhibiting the response to interleukin 2 (IL-2). Its mode of action differs from that of other immunosuppressants (SN Sehga, Clin Biochem, 31:335, 1998) most notably by not being a calcineurin inhibitor. Its inhibitory action is mediated via a cytosolic protein, FK-binding protein 12. Sirolimus is variably absorbed; levels need to monitored to achieve the therapeutic target while avoiding toxic levels. Sirolimus is marketed under the trade name Rapamune. Source: Regenstrief LOINC

Fully-Specified Name

Component
Sirolimus
Property
SCnc
Time
Pt
System
Bld
Scale
Qn
Method
IA

Additional Names

Short Name
Sirolimus Bld IA-sCnc
Display Name
Sirolimus IA (Bld) [Moles/Vol]
Consumer Name Alpha Get Info
Sirolimus, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Sirolimus:Concentración de sustancia:Punto temporal:Sangre:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Sirolimus:Concentración de sustancias:Punto temporal:Sangre:Cuantitativo:Inmunoensayo
et-EE Estonian (Estonia) Siroliimus:SCnc:Pt:B:Qn:IA
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Veri
fr-FR French (France) Sirolimus:Moles/Volume:Ponctuel:Sang:Numérique:Immunoanalyse
fr-BE French (Belgium) Sirolimus:Concentration de substance:Temps ponctuel:Sang:Quantitatif:IA
fr-CA French (Canada) Sirolimus:Concentration de substance:Temps ponctuel:Sang:Quantitatif:IA
it-IT Italian (Italy) Sirolimus:SCnc:Pt:Sangue:Qn:IA
Synonyms: Concentrazione di Sostanza Immunoassay Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) sirolimus:mol/volume:moment:bloed:kwantitatief:immunoassay
Synonyms: IA
ru-RU Russian (Russian Federation) Сиролимус:МолКонц:ТчкВрм:Кр:Колич:IA
Synonyms: Количественный Кровь Молярность;Молярная объёмная концентрация Рапамицин Точка во времени;Момент
tr-TR Turkish (Turkey) Sirolimus:SubKons:Zmlı:Kan:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CN Chinese (China) 西罗莫司:物质的量浓度:时间点:全血:定量型:免疫测定法
Synonyms: 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 瑞帕霉素;雷帕霉素 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血;血液

Example Units

Unit Source
nmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96462-7