96462-7
Sirolimus [Moles/volume] in Blood by Immunoassay
Active
Part Description
LP21368-3 Sirolimus
Sirolimus, also known as rapamycin, is a macrolide compound that inhibits lymphocyte proliferation and is used as an immunosuppressant to prevent rejection in organ transplantation. It inhibits T-cell activation and proliferation by inhibiting the response to interleukin 2 (IL-2). Its mode of action differs from that of other immunosuppressants (SN Sehga, Clin Biochem, 31:335, 1998) most notably by not being a calcineurin inhibitor. Its inhibitory action is mediated via a cytosolic protein, FK-binding protein 12. Sirolimus is variably absorbed; levels need to monitored to achieve the therapeutic target while avoiding toxic levels. Sirolimus is marketed under the trade name Rapamune.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Sirolimus
- Property
- SCnc
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
- IA
Additional Names
- Short Name
- Sirolimus Bld IA-sCnc
- Display Name
- Sirolimus IA (Bld) [Moles/Vol]
- Consumer Name Alpha Get Info
- Sirolimus, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.69
- Last Updated
- Version 2.69
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Sirolimus: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Sirolimus: |
et-EE | Estonian (Estonia) | Siroliimus: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Veri |
fr-FR | French (France) | Sirolimus: |
fr-BE | French (Belgium) | Sirolimus: |
fr-CA | French (Canada) | Sirolimus: |
it-IT | Italian (Italy) | Sirolimus: Synonyms: Concentrazione di Sostanza Immunoassay Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue |
nl-NL | Dutch (Netherlands) | sirolimus: Synonyms: IA |
ru-RU | Russian (Russian Federation) | Сиролимус: Synonyms: Количественный Кровь Молярность; |
tr-TR | Turkish (Turkey) | Sirolimus: Synonyms: İmmünölçüm, immünoassay |
zh-CN | Chinese (China) | 西罗莫司: Synonyms: 克分子浓度; |
Example Units
Unit | Source |
---|---|
nmol/L | Example UCUM Units |
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