Version 2.78

Term Description

A free copper level is calculated based on the difference between total copper and ceruloplasmin measurements, where the ceruloplasmin level represents the bound portion of circulating copper. In patients with Wilson's disease that is pre-symptomatic or adequately controlled, the free copper level is within normal range, but in symptomatic patients, it is typically elevated. Increasing free copper levels in a patient with previously normal levels may indicate a change in compliance with therapy or a growth spurt or change in diet requiring therapy adjustment. PMID: 12662398 This term represents the calculated result for free copper level as a fraction of the total copper measurement.
Source: Regenstrief LOINC

Part Description

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

Fully-Specified Name

Component
Copper.free/Copper.total
Property
MFr
Time
Pt
System
Ser/Plas
Scale
Qn
Method
Calculated

Additional Names

Short Name
Copper free/Total copper MFr SerPl Calc
Display Name
Copper free/Total copper Calc [Mass fraction]
Consumer Name Alpha Get Info
Copper free/Total copper, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation
Both

Formula (Readable)

(Total copper - ceruloplasmin)/Total copper

Member of these Panels

LOINC Long Common Name
105459-2 Copper panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Kupfer, freies (kalkuliert)
es-ES Spanish (Spain) Cobre libre/Cobre total:Fracción de masa:Punto temporal:Suero o Plasma:Qn:Calculado
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Cobre.libre/Copper.total:Fracción de masa:Punto temporal:Suero o Plasma:Cuantitativo:Calculado
fr-FR French (France) Cuivre libre/cuivre total:Fraction massique:Ponctuel:Sérum/Plasma:Numérique:Résultat calculé
it-IT Italian (Italy) Rame.libero/Rame.totale:MFr:Pt:Siero/Plasma:Qn:Calcolato
Synonyms: Frazione di massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) koper.vrij/koper.totaal:massafractie:moment:serum of plasma:kwantitatief:berekend
zh-CN Chinese (China) 铜.游离型/铜.总计:质量分数:时间点:血清/血浆:定量型:计算法
Synonyms: Cu MFr 全体数量 全部 共计 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 总 总和 总数 总量 总额 时刻;随机;随意;瞬间 毒品 毒品类 汇总 游离 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆 计算;计算型方法 铜（Cu）.总计;总铜（Cu） 铜（Cu）.游离型;游离铜（Cu） 非蛋白结合型 非蛋白质结合型

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96463-5