LOINC
Version 2.73

96484-1Neuronal intermediate filament heavy chain IgG Ab [Presence] in Serum by Cell binding immunofluorescent assayActive

Part Descriptions

LP420695-1   Neuronal intermediate filament heavy chain Ab.IgG
Neuronal intermediate filaments (NIFs) are a group of neurofilaments that include light, medium, and heavy subunits as well as alpha-internexin. Accumulation of these filaments in the central nervous system is associated with a variety of progressive neurodegenerative disorders. [PMID:15161649] Antibodies to NIFs are associated with paraneoplastic disorders affecting the central nervous system, including those associated with cerebellar ataxia and/or encephalopathy. [PMID:30282771] Source: Regenstrief LOINC

LP269367-1   CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC

Fully-Specified Name

Component
Neuronal intermediate filament heavy chain Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
CBA IFA

Additional Names

Short Name
NIF-H IgG Ser Ql CBA IFA
Display Name
Neuronal intermediate filament heavy chain IgG Cell binding immunofluorescent assay Ql (S)
Consumer Name Alpha
Neuronal intermediate filament heavy chain IgG antibody, Blood

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation
Observation

Language Variants Get Info

zh-CNChinese (China)
神经中间丝重链 抗体.IgG:存在情况或阈值:时间点:血清:序数型:CBA IFA
fr-FRFrench (France)
NIFs à chaine lourde anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence CBA
it-ITItalian (Italy)
Neuronale, filamento intermedio catena pesante Ab.IgG:PrThr:Pt:Siero:Ord:CBA IFA
es-MXSpanish (Mexico)
Ab.IgG de cadena pesada de filamento intermedio neuronal:Presencia o umbral:Punto temporal:Suero:Ordinal:Ensayo inmunofluorescente de unión a células
es-ESSpanish (Spain)
Cadena pesada de filamento intermedio neuronal IgG:PrThr:Punto temporal:Suero:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96484-1