96763-8

SARS-CoV-2 (COVID-19) E gene [Presence] in Respiratory system specimen by NAA with probe detection

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Term Description

Qualitative detection of nucleic acids within the envelope (E) gene specific for SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection.

Reference Information

Type	Source	Reference
Webcontent	Lab Tests Online^®Copyright Copyright © 2021 Lab Tests Online. All rights reserved.	Coronavirus (COVID-19) Testing
Mapping Guidance	LOINC	Take caution when mapping LOINC codes to molecular tests for SARS coronaviruses that target nucleic acids within the E gene. Such assays detect either SARS-related coronavirus or SARS-CoV-2, depending on the targeted region within the E gene. Assays that are non-specific to only SARS-CoV-2 may say they are "positive" for SARS-CoV-2, but only because it is the primary circulating virus during the pandemic. These assays actually detect any SARS-related coronaviruses since they target a region in the E gene that contains sequence homology to other known coronaviruses. Other assays target a region in the E gene that is specific for SARS-CoV-2. The LIVD file contains current LOINC code mappings to many IVD tests [https://www.cdc.gov/csels/dls/sars-cov-2-livd-codes.html]. You may also contact the manufacturer directly to verify LOINC code mappings.

Fully-Specified Name

Component: SARS coronavirus 2 E gene
Property: PrThr
Time: Pt
System: Respiratory System Specimen
Scale: Ord
Method: Probe.amp.tar

Additional Names

Long Common Name: SARS-CoV-2 (COVID-19) E gene [Presence] in Respiratory system specimen by NAA with probe detection
Short Name: SARS-CoV-2 E gene Resp Ql NAA+probe
Display Name: SARS-CoV-2 (COVID-19) E gene NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info: SARS-CoV-2 (COVID-19) E gene, Respiratory system specimen

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.70
Last Updated: Version 2.75 (MAJ)
Change Reason: Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
95941-1	Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
96094-8	SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1	SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group	Group Name
LG51017-8	SARSCoV2 detection
LG51019-4	SARSCoV2 molecular detection

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	SARS-Coronavirus 2 E-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Γονίδιο Ε κορωνοϊού SARS 2:PrThr:Pt:Δείγμα αναπνευστικού συστήματος:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: E PrThr Γονίδιο Γονίδιο Ε κορωνοϊού SARS 2 Κορωνοϊός Κορωνοϊός SARS Κορωνοϊός SARS 2
es-ES	Spanish (Spain)	Gen E del SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX	Spanish (Mexico)	Gen del coronavirus 2 E del SARS:PrThr:Punto temporal:Respiratorio:Ordinal:Probe.amp.tar
fr-CA	French (Canada)	Coronavirus SARS-CoV-2 gène E:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
fr-FR	French (France)	Coronavirus SARS-CoV-2 gène E:Présence/Seuil:Ponctuel:Échantillon du système respiratoire:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	SARS coronavirus 2, gene E:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene E di SARS coronavirus 2;gene E di SARS-CoV-2 (COVID-19) Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	SARS-CoV-2 E-gen:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
uk-UA	Ukrainian (Ukraine)	SARS коронавірус 2 Ген E:Наявність або Поріг:МоментЧасу:Зразок з респіраторної системи:Порядково:Зонд-детекція. цільова аміпліфікація НК Synonyms: 2019 Novel Coronavirus; 2019-nCoV; 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; Breathing; Corona virus; COVID19; COVID-19; DNA NUCLEIC ACID PROBE; DNA probe; ID; II; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Lungs; Microbiology; NAA+probe; NAAT; NASBA; Nucleic acid sequence based analysis; Ordinal; PCR; Point in time; Polymerase chain reaction; PR; Probe amp; Probe with ampification; Probe with target amplification; QBR; QL; Qual; Qualitative; Random; RS; SARS Coronavirus 1; SARS-CoV; SARS-CoV-1; SARS-CoV-2; SARS-CoV-2 E gene; Screen; SDA; Severe Acute Respiratory Syndrome; Spec; Strand Displacement Amplification; TMA; Transcription mediated amplification; Viral Pneumonias; Wuhan coronavirus
zh-CN	Chinese (China)	SARS 冠状病毒 2 E 基因:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向 Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ E 型 II SARS 冠状病毒 2 E 基因;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向受检物呼吸道标本（样品、样本）;呼吸系统标本（样品、样本）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间样品样本经过扩增的脱氧核糖核酸探针试样遗传基因;遗传因子;吉恩;生物基因

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