Version 2.76

Term Description

Qualitative detection of nucleic acids within the envelope (E) gene specific for SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection.
Source: Regenstrief LOINC

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Coronavirus (COVID-19) Testing
Mapping Guidance LOINC Take caution when mapping LOINC codes to molecular tests for SARS coronaviruses that target nucleic acids within the E gene. Such assays detect either SARS-related coronavirus or SARS-CoV-2, depending on the targeted region within the E gene. Assays that are non-specific to only SARS-CoV-2 may say they are "positive" for SARS-CoV-2, but only because it is the primary circulating virus during the pandemic. These assays actually detect any SARS-related coronaviruses since they target a region in the E gene that contains sequence homology to other known coronaviruses. Other assays target a region in the E gene that is specific for SARS-CoV-2. The LIVD file contains current LOINC code mappings to many IVD tests [https://www.cdc.gov/csels/dls/sars-cov-2-livd-codes.html]. You may also contact the manufacturer directly to verify LOINC code mappings.

Fully-Specified Name

Component
SARS coronavirus 2 E gene
Property
PrThr
Time
Pt
System
Respiratory System Specimen
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
SARS-CoV-2 E gene Resp Ql NAA+probe
Display Name
SARS-CoV-2 (COVID-19) E gene NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info
SARS-CoV-2 (COVID-19) E gene, Respiratory system specimen

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.75
Change Reason
Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
95941-1 Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
96094-8 SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1 SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG51017-8 SARSCoV2 detection
LG51019-4 SARSCoV2 molecular detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) SARS-Coronavirus 2 E-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Respirationstrakt:Ordinal:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Gen E del SARS-CoV-2 (COVID-19):PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida
Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX Spanish (Mexico) Gen del coronavirus 2 E del SARS:PrThr:Punto temporal:Respiratorio:Ordinal:Probe.amp.tar
fr-FR French (France) Coronavirus SARS-CoV-2 gène E:Présence/Seuil:Ponctuel:Spécimen du système respiratoire:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) SARS coronavirus 2, gene E:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene E di SARS coronavirus 2;gene E di SARS-CoV-2 (COVID-19) Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) SARS-CoV-2 E-gen:aanwezigheid:moment:ademhalingsstelsel:ordinaal:probe-detectie
Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96763-8