Version 2.80

Term Description

Quantitative detection (Cq value) of nucleic acids within the envelope (E) gene specific for SARS coronavirus 2 (SARS-CoV-2) in respiratory specimens by nucleic acid amplification with probe-based detection.

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Coronavirus (COVID-19) Testing
Mapping Guidance LOINC Take caution when mapping LOINC codes to molecular tests for SARS coronaviruses that target nucleic acids within the E gene. Such assays detect either SARS-related coronavirus or SARS-CoV-2, depending on the targeted region within the E gene. Assays that are non-specific to only SARS-CoV-2 may say they are "positive" for SARS-CoV-2, but only because it is the primary circulating virus during the pandemic. These assays actually detect any SARS-related coronaviruses since they target a region in the E gene that contains sequence homology to other known coronaviruses. Other assays target a region in the E gene that is specific for SARS-CoV-2. The LIVD file contains current LOINC code mappings to many IVD tests [https://www.cdc.gov/csels/dls/sars-cov-2-livd-codes.html]. You may also contact the manufacturer directly to verify LOINC code mappings.

Fully-Specified Name

Component
SARS coronavirus 2 E gene
Property
ThreshNum
Time
Pt
System
Respiratory System Specimen
Scale
Qn
Method
Probe.amp.tar

Additional Names

Long Common Name
SARS-CoV-2 (COVID-19) E gene [Cycle Threshold #] in Respiratory system specimen by NAA with probe detection
Short Name
SARS-CoV-2 E gene Ct Resp Qn NAA+probe
Display Name
SARS-CoV-2 (COVID-19) E gene NAA+probe (Respiratory system specimen) [ThreshNum]
Consumer Name Alpha Get Info
SARS-CoV-2 (COVID-19) E gene, Respiratory system specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.75 (MAJ)
Change Reason
Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
96094-8 SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1 SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG51017-8 SARSCoV2 detection
LG51019-4 SARSCoV2 molecular detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) SARS-Coronavirus 2 E-Gen:Ct-Wert:Zeitpunkt:Probenmaterial vom Respirationstrakt:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
el-GR Greek (Greece) Γονίδιο Ε κορωνοϊού SARS 2:ThreshNum:Pt:Δείγμα αναπνευστικού συστήματος:Qn:Ανιχνευτής.ενίσχυση.στόχου
Synonyms: E ThreshNum Γονίδιο Γονίδιο Ε κορωνοϊού SARS 2 Κορωνοϊός Κορωνοϊός SARS Κορωνοϊός SARS 2
es-ES Spanish (Spain) Gen E del SARS-CoV-2 (COVID-19):ThreshNnum:Punto temporal:Muestra del sistema respiratorio:Qn:Sonda con amplificación dirigida
Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX Spanish (Mexico) Gen del coronavirus 2 E del SARS:ThreshNum:Punto temporal:Respiratorio:Cuantitativo:Probe.amp.tar
fr-FR French (France) Coronavirus SARS-CoV-2 gène E:Cycle seuil:Ponctuel:Échantillon du système respiratoire:Numérique:PCR amplification de cible
it-IT Italian (Italy) SARS coronavirus 2, gene E:Thresnum:Pt:Campione da Sistema Respiratorio:Qn:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene E di SARS coronavirus 2;gene E di SARS-CoV-2 (COVID-19) Limite di soglia Microbiologia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) SARS-CoV-2 E-gen:drempelwaarde nummer:moment:respiratoir monster:kwantitatief:probe-detectie
Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel
zh-CN Chinese (China) SARS 冠状病毒 2 E 基因:阈值循环圈数:时间点:呼吸系统标本:定量型:探针法.基因扩增.靶向
Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ E 型 II SARS 冠状病毒 2 E 基因;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 受检物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 呼吸道标本（样品、样本）;呼吸系统标本（样品、样本） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 样品 样本 界值数;界限数;阀值数;临界值数;阈值循环数;阈值数;达到阈值时的循环圈数;荧光信号到达设定阈值时所经历的循环数;Ct 值;Cycle threshold;循环阈值 经过扩增的 脱氧核糖核酸探针 试样 遗传基因;遗传因子;吉恩;生物基因

Example Units

Unit Source
{Ct_value} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96764-6