Version 2.78

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus Ab.IgM Index
Property
ACnc
Time
Pt
System
Ser+CSF
Scale
Qn
Method

Additional Names

Short Name
VZV IgM Index Ser+CSF-aCnc
Display Name
VZV IgM index Qn (S+CSF)
Consumer Name Alpha Get Info
Varicella zoster virus (VZV; Chickenpox) IgM index, Serum+Cerebrospinal fluid

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation
Observation

Formula (Readable)

VZV IgM Index = (CSF VZV IgM/CSF total IgM)/(Serum VZV IgM/Serum total IgM)

Member of these Groups Get Info

LOINC Group Group Name
LG32750-8 Varicella zoster virus

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Varizella-Zoster-Virus IgM AK-Index
de-DE German (Germany) Varicella-Zoster-Virus Ak.IgM-Index:Arbiträre Konzentration:Zeitpunkt:Serum und Liquor:Quantitativ:
Synonyms: Human alphaherpesvirus 3; VZV; Zerebrospinalflüssigkeit
es-ES Spanish (Spain) Virus Varicella zoster Indice IgM:Concentración arbitraria:Punto temporal:Suero y Líquido Cefalorraquideo simultaneamente:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Índice Ab.IgM del virus de la varicela zóster:ACnc:Punto temporal:Ser + CSF:Cuantitativo:
et-EE Estonian (Estonia) Tuulerõugeviirus Antikehad.IgM indeks:Acnc:Pt:S+CSF:Qn:
Synonyms: Immuunglobuliin M Juhuslik Kvantitatiivne Liikvor Seerum Seerum ja liikvor
fr-CA French (Canada) Virus varicelle-zona, Indice IgM:Concentration arbitraire:Temps ponctuel:Sérum+LCR:Quantitatif:
fr-BE French (Belgium) Virus varicelle-zona Anticorps. Indice IgM:Concentration arbitraire:Temps ponctuel:Sérum+LCR:Quantitatif:
Synonyms: Anticorps VZV
fr-FR French (France) Varicelle zona virus Ac IgM index:Arbitraire/Volume:Ponctuel:Sérum+Liquide céphalorachidien:Numérique:
it-IT Italian (Italy) Varicella zoster, virus Ab.indice IgM:ACnc:Pt:Siero+LCS:Qn:
Synonyms: Anticorpi IgM Anticorpi Indice delle IgM anticorpo Concentrazione Arbitraria Liquido cerebrospinale Microbiologia Punto nel tempo (episodio) Siero Siero & LCS Virus della varicella zoster
nl-NL Dutch (Netherlands) varicella-zostervirus As.IgM-index:eenheid/volume:moment:serum en liquor cerebrospinalis:kwantitatief:
Synonyms: antistof; antilichaam Varicella zoster virus
ru-RU Russian (Russian Federation) Varicella zoster вирус Ат.IgM индекс:ПроизвКонц:ТчкВрм:Сыв+ЦСЖ:Колич:
Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Сыворотка и цереброспинальная жидкость Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Varicella zoster virüsü Ab.IgM index:SçKons:Zmlı:Ser+BOS:Kant:
Synonyms: Ak Ak.IgM Ak.IgM index
zh-CN Chinese (China) 水痘带状疱疹病毒 抗体.IgM 指数:任意型浓度:时间点:血清+脑脊液:定量型:
Synonyms: Ab.IgM 指数;IgM 指数;抗体 IgM 指数 Ab.IgM;IgM;抗体 IgM Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 HHV-3 Ab HHV-3 Ab.IgM HHV-3 抗体 HHV-3 抗体.IgM HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 VZV Ab VZV Ab.IgM VZV 抗体 VZV 抗体.IgM 人类疱疹病毒 3 型 Ab 人类疱疹病毒 3 型 Ab.IgM 人类疱疹病毒 3 型抗体 人类疱疹病毒 3 型抗体.IgM 人类疱疹病毒 III 型 Ab 人类疱疹病毒 III 型 Ab.IgM 人类疱疹病毒 III 型抗体 人类疱疹病毒 III 型抗体.IgM 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 免疫球蛋白 M 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 水痘带状疱疹病毒 Ab 水痘带状疱疹病毒 Ab.IgM 水痘带状疱疹病毒 IgM 水痘病毒 Ab 水痘病毒 Ab.IgM 水痘病毒抗体 水痘病毒抗体.IgM 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清 & 脑脊液;血清 & 脑脊髓液;血清+脑脊髓液;血清与脑脊液;血清与脑脊髓液

Example Units

Unit Source
{Index_val} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96960-0