97523-5

Hepatitis A virus RNA [Presence] in Specimen by NAA with probe detection

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Part Descriptions

LP16708-7 Hepatitis A virus
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.

Although HAV is excreted in the feces towards the end of the incubation period, specific diagnosis is made by the detection of HAV-specific IgM antibodies in the blood. IgM antibody is only present in the blood following an acute hepatitis A infection. It is detectable from one to two weeks after the initial infection and persists for up to 14 weeks. The presence of IgG antibody in the blood means that the acute stage of the illness is past and the person is immune to further infection. IgG antibody to HAV is also found in the blood following vaccination and tests for immunity to the virus are based on the detection of this antibody. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hepatitis A virus (Wikipedia)

LP16708-7 Hepatitis A virus
Hepatitis A virus (HAV) is a small, non-enveloped single-stranded RNA virus that belongs to the Picornaviridae family, genus Hepatovirus. HAV has six genotypes (I to VI) in which genotypes I to III are human isolates and IV to VI are only simian isolates. Genotypes I to III are subdivided into groups A and B. Genotype I is the most frequently reported. PMID: 15914081 The clinical manifestations of HAV infection can vary significantly and range from asymptomatic infection, usually seen in young children, to fulminant hepatitis, which can result in death. HAV has a global distribution, and transmission primarily occurs by the fecal-oral route. The risk of HAV transmission through blood products is very low, but there have been some reports of transmission through plasma products, mainly coagulation factors. PMID: 12186933 PMID: 1318940 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Hepatitis A virus RNA:PrThr:Pt:XXX:Ord:Probe.amp.tar
Long Common Name: Hepatitis A virus RNA [Presence] in Specimen by NAA with probe detection
Short Name: HAV RNA Spec Ql NAA+probe
Display Name: HAV RNA NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info: Hepatitis A virus (HAV), Specimen

Part Model Get Info

Component
Hepatitis A virus RNA
LP38319-7
- Analyte
  Hepatitis A virus RNA
  LP38319-7
  - Component Numerator
    Hepatitis A virus RNA
    LP38319-7
    - Component Numerator Core
      Hepatitis A virus
      LP16708-7
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Probe.amp.tar
LP6464-4

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.70
Last Updated: Version 2.70 (ADD)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG32762-3	Hepatitis A virus

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus hepatitidy A RNA:Přítomnost nebo práh:Časový bod:XXX:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-DE	German (Germany)	Hepatitis-A-Virus RNA:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Zielfragmentamplifikation mit Sondendetektion Synonyms: Hepatovirus A; HAV
el-GR	Greek (Greece)	Ιός Ηπατίτιδας Α RNA:PrThr:Pt:XXX:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: A MICRO Ord PrThr Pt RNA XXX Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ιός Ιός ηπατίτιδας Α
es-ES	Spanish (Spain)	Virus de la Hepatitis A RNA:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	ARN del virus de la hepatitis A:PrThr:Punto temporal:No especificado:Ordinal:Probe.amp.tar
fr-BE	French (Belgium)	Virus de l'hépatite A ARN:PrThr:Temps ponctuel:XXX:Ordinal:Sonde avec amplification de la cible Synonyms: HVA
fr-CA	French (Canada)	Virus de l'hépatite A ARN:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Sonde avec amplification de la cible
fr-FR	French (France)	Hépatite A virus ARN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Epatite A, virus RNA:PrThr:Pt:XXX:Ord:Sonda.amp.tar Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite A
nl-NL	Dutch (Netherlands)	Hepatitis A-virus RNA:aanwezigheid:moment:XXX:ordinaal:probe-detectie Synonyms: probe.amp.tar
pl-PL	Polish (Poland)	Wirus zapalenia wątroby typu A RNA:granica wykrywalności:punkt w czasie:XXX:uporządkowany:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy RNA wirusa zapalenia wątroby typu A
ru-RU	Russian (Russian Federation)	Гепатита А вирус РНК:PrThr:ТчкВрм:XXX:Пор:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hepatit A virüsü RNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf Synonyms: Mevcut
zh-CN	Chinese (China)	甲型肝炎病毒 RNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向 Synonyms: A 型 HAV RNA HAV;Hep A;甲型肝炎;甲肝;甲肝病毒;肝炎病毒 A 型 Hep A RNA 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项传染性肝炎传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 甲肝病毒 RNA 经过扩增的肝肝炎病毒 A 型 RNA 脱氧核糖核酸探针

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.