LOINC
Version 2.70

97911-2Endogenous thrombin potential [Area under the curve] in Platelet poor plasma by Chromogenic method --after addition of factor VIII AbActive

Term Description

The endogenous thrombin potential (ETP) is the area under the curve of a thrombin generation test (TGT). It represents thrombin's total enzyme activity and is the most predictive of bleeding and/or thrombosis risk out of all the TGT measurements. [PMID: 21262433] Measuring the ETP in the presence of Factor VIII antibodies is done to help determine the contribution of Factor VIII to the ETP. If the ETP is significantly decreased in the presence of Factor VIII antibodies, that indicates that Factor VIII had a significant contribution to the baseline ETP. If the ETP does not decrease, then Factor VIII did not have a large contribution. [PMID: 12871369]
Source: Regenstrief LOINC

Part Description

LP14587-7   Factor VIII
Blood-coagulation factor VIII; Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Endogenous thrombin potential^after addition of Factor VIII Ab
Property
TmSCnc
Time
Pt
System
PPP
Scale
Qn
Method
Chromo

Additional Names

Short Name
ETP p FVIII Ab PPP Chro-AUC
Display Name
Endogenous thrombin potential after addition of factor VIII Ab Chromogenic method (PPP) [Area under the curve]
Consumer Name Alpha
Endogenous thrombin potential after addition of factor VIII Ab, Blood

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
97915-3 Thrombin generation test panel - Platelet poor plasma

Example Units

Unit Source
nmol.min/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=97911-2