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Term Description

The endogenous thrombin potential (ETP) is the area under the curve of a thrombin generation test (TGT). It represents thrombin's total enzyme activity and is the most predictive of bleeding and/or thrombosis risk out of all the TGT measurements. PMID: 21262433 Measuring the ETP in the presence of Factor VIII antibodies is done to help determine the contribution of Factor VIII to the ETP. If the ETP is significantly decreased in the presence of Factor VIII antibodies, that indicates that Factor VIII had a significant contribution to the baseline ETP. If the ETP does not decrease, then Factor VIII did not have a large contribution. PMID: 12871369

Part Description

LP14587-7   Factor VIII
Blood-coagulation factor VIII; Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin. Source: National Library of Medicine, MeSH 2006

LOINC Names Get Info

Fully-Specified Name
Endogenous thrombin potential^after addition of Factor VIII Ab:TmSCnc:Pt:PPP:Qn:Chromo
Long Common Name
Endogenous thrombin potential [Area under the curve] in Platelet poor plasma by Chromogenic method --after addition of factor VIII Ab
Short Name
ETP p FVIII Ab PPP Chro-AUC
Display Name
Endogenous thrombin potential after addition of factor VIII Ab Chromogenic method (PPP) [Area under the curve]
Consumer Name Alpha Get Info
Endogenous thrombin potential after addition of factor VIII Ab, Blood

Part Model Get Info

  • Component
    Endogenous thrombin potential^after addition of Factor VIII Ab
    LP427304-3
    • Analyte
      Endogenous thrombin potential
      LP426525-4
      • Component Numerator
        Endogenous thrombin potential
        LP426525-4
        • Component Numerator Core
          Endogenous thrombin potential
          LP426525-4
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      after addition of factor VIII Ab
      LP426526-2
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    TmSCnc
    LP411318-1
  • Time
    Pt
    LP6960-1
  • System
    PPP
    LP7494-0
    • System Core
      PPP
      LP7494-0
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    Chromo
    LP6256-4

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70 (ADD)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
97915-3Thrombin generation test panel - Platelet poor plasma

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Trombinový potenciál endogenní^Po přidání faktoru VIII Ab:Plocha pod křivkou (látková koncentrace):Časový bod:Plazma chudá na trombocyty:Kvantitativní:Chromogenní (enzymatický) test
el-GRGreek (Greece)Ενδογενές δυναμικό θρομβίνης^κατόπιν προσθήκης αντισωμάτων έναντι του παράγοντα VIII:TmSCnc:Pt:PPP:Qn:Chromo
Synonyms: Chromo COAG PPP Pt Qn TmSCnc Ενδογενές δυναμικό θρομβίνης κατόπιν προσθήκης αντισωμάτων έναντι του παράγοντα VIII Παράγοντας VIII
es-ESSpanish (Spain)Potencial de trombina endógena^tras la adición de Factor VIII Ab:Área bajo la curva:Punto temporal:Plasma pobre en plaquetas:Qn:Cromogénico ( Enzima)
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Potencial de trombina endógena^después de la adición de factor VIII Ab:TmSCnc:Punto temporal:PPP:Cuantitativo:Cromo
fr-FRFrench (France)Potentiel thrombine endogène^Après addition de facteur VIII anticorps:Temps*Moles/Volume:Ponctuel:Plasma pauvre en plaquettes:Numérique:Technique chromogénique
it-ITItalian (Italy)potenziale endogeno di trombina^dopo aggiunta di fattore VIII Ab:TmSCnc:Pt:PPP:Qn:Cromo
Synonyms: Cromogenico (Enzima) ETP Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione
zh-CNChinese (China)内源性凝血酶生成潜力^在添加凝血因子 VIII 抗体之后:曲线下面积:时间点:贫血小板血浆:定量型:凝血因子酶学测定法
Synonyms: FVIII TmSCnc;曲线下的面积;AUC 乏血小板血浆;Platelet poor plasma;PPP 凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程 凝血因子 凝血因子Ⅷ;因子 VIII;因子Ⅷ;血液制品 - 凝血因子 VIII;血液制品 - 凝血因子Ⅷ;血液制品 - 因子 VIII;血液制品 - 因子Ⅷ 凝血因子发色测定方法;凝血因子发色测定法;凝血因子酶学测定方法;发色法;发色测定方法;发色测定法;显色法;显色测定方法;显色测定法;酶学法;酶学测定方法;酶学测定法;酶法 凝血酶生成潜力;ETP;内源凝血酶能力;内源凝血酶生成潜力 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 因子 8 因子 VIII 因素 在添加（加入）凝血因子 VIII （凝血因子Ⅷ、因子 VIII、因子Ⅷ）抗体（Ab）之后（后） 时刻;随机;随意;瞬间 系数 纤维蛋白酶

Example Units

UnitSource
nmol.min/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=97911-2