LOINC
Version 2.70

97990-6von Willebrand factor (vWf) cleaving protease actual/normal in Platelet poor plasma by ImmunoassayActive

Part Description

LP32458-9   von Willebrand factor cleaving protease
von Willebrand factor (vWF) cleaving protease, or ADAMTS13, is a metalloprotease that cleaves vWF and thereby limits platelet aggregation and formation of microthrombi. vWF cleaving protease inhibitors can decrease the protease activity and/or more rapidly remove the enzyme from the circulation. Such inhibitors are one cause of thrombotic thrombocytopenic purpura (TTP), a disorder characterized by thrombocytopenia, anemia, fever, and neurologic and renal abnormalities. Idiopathic TTP is often due to anti-ADAMTS13 autoantibodies, while inherited TTP is an autosomal recessive disorder due to mutations in the ADAMTS13 gene that lead to impaired protease function. Work-up of patients with TTP can include vWF cleaving protease activity and, if that activity is low, inhibitor screen followed by quantification. [PMID: 18756543] Source: Regenstrief LOINC

Fully-Specified Name

Component
von Willebrand factor cleaving protease actual/normal
Property
RelCCnc
Time
Pt
System
PPP
Scale
Qn
Method
IA

Additional Names

Short Name
vWF Cp Act/Nor PPP IA
Display Name
vWf cleaving protease actual/normal IA (PPP) [Rel catalytic activity/Vol]
Consumer Name Alpha
vWf cleaving protease actual/normal, Blood

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
von Willebrand 因子裂解蛋白酶 实际的/正常的:相对催化浓度:时间点:贫血小板血浆:定量型:免疫测定法
nl-NLDutch (Netherlands)
von Willebrand-factor cleaving protease gemeten/normaal:relatieve enzymatische activiteit/normaal:moment:plaatjesarm plasma:kwantitatief:immunoassay
fr-BEFrench (Belgium)
Protéase de clivage du Facteur von Willebrand Mesuré/normal:Concentration catalytique relative:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:IA
fr-CAFrench (Canada)
Protéase de coupage Facteur von Willebrand , Mesuré/normal:Concentration catalytique relative:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:IA
it-ITItalian (Italy)
von Willebrand, proteasi di taglio fattore , effettivo/normale:RelCCnc:Pt:PPP:Qn:IA
ru-RURussian (Russian Federation)
von Willebrand фактор (vWf) расщепляющая протеаза актуальный/нормальный:ОтнКаталКонц:ТчкВрм:ОПП:Колич:IA
es-ESSpanish (Spain)
Proteasa divisora del Factor de von Willebrand actual/normal:Concentración catalítica relativa:Punto temporal:Plasma pobre en plaquetas:Qn:IA
tr-TRTurkish (Turkey)
von Willebrand faktörü parçalıyıcı proteaz gerçek/normal:GörKtlKons:Zmlı:TFkP:Kant:İA

Example Units

Unit Source
% Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=97990-6