Log In

Part Description

LP32458-9   von Willebrand factor cleaving protease
von Willebrand factor (vWF) cleaving protease, or ADAMTS13, is a metalloprotease that cleaves vWF and thereby limits platelet aggregation and formation of microthrombi. vWF cleaving protease inhibitors can decrease the protease activity and/or more rapidly remove the enzyme from the circulation. Such inhibitors are one cause of thrombotic thrombocytopenic purpura (TTP), a disorder characterized by thrombocytopenia, anemia, fever, and neurologic and renal abnormalities. Idiopathic TTP is often due to anti-ADAMTS13 autoantibodies, while inherited TTP is an autosomal recessive disorder due to mutations in the ADAMTS13 gene that lead to impaired protease function. Work-up of patients with TTP can include vWF cleaving protease activity and, if that activity is low, inhibitor screen followed by quantification. PMID: 18756543 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
von Willebrand factor cleaving protease actual/normal:RelCCnc:Pt:PPP:Qn:IA
Long Common Name
von Willebrand factor (vWf) cleaving protease actual/normal in Platelet poor plasma by Immunoassay
Short Name
vWF Cp Act/Nor PPP IA
Display Name
vWf cleaving protease actual/normal IA (PPP) [Rel catalytic activity/Vol]
Consumer Name Alpha Get Info
vWf cleaving protease actual/normal, Blood

Part Model Get Info

  • Component
    von Willebrand factor cleaving protease actual/normal
    LP229927-1
    • Analyte
      von Willebrand factor cleaving protease actual/normal
      LP229927-1
      • Component Numerator
        von Willebrand factor cleaving protease actual/normal
        LP229927-1
        • Component Numerator Core
          von Willebrand factor cleaving protease
          LP32458-9
        • Component Numerator Core Suffix
          actual/normal
          LP29333-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    RelCCnc
    LP31739-3
  • Time
    Pt
    LP6960-1
  • System
    PPP
    LP7494-0
    • System Core
      PPP
      LP7494-0
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    IA
    LP217197-5

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.70
Last Updated
Version 2.70 (ADD)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)von Willebrandův faktor štěpící proteáza aktuální/normální:Relativní katalytická koncentrace:Časový bod:Plazma chudá na trombocyty:Kvantitativní:Imunoanalýza
de-DEGerman (Germany)von-Willebrand-Faktor-spaltende Protease Messwert/Normalwert:Relative katalytische Konzentration:Zeitpunkt:Thrombozytenarmes Plasma:Quantitativ:Immunoassay
el-GRGreek (Greece)πρωτεάση διάσπασης παράγοντα Von Willebrand πραγματικό/φυσιολογικό:RelCCnc:Pt:PPP:Qn:IA
Synonyms: COAG IA PPP Pt Qn RelCCnc παράγοντας Von Willebrand πραγματικό/φυσιολογικό πρωτεάση διάσπασης παράγοντα Von Willebrand
es-MXSpanish (Mexico)proteasa de escisión del factor von Willebrand real / normal:RelCCnc:Punto temporal:PPP:Cuantitativo:I A
es-ESSpanish (Spain)Proteasa divisora del Factor de von Willebrand actual/normal:Concentración catalítica relativa:Punto temporal:Plasma pobre en plaquetas:Qn:IA
Synonyms: Cuantitativo
fr-BEFrench (Belgium)Protéase de clivage du Facteur von Willebrand Mesuré/normal:Concentration catalytique relative:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:IA
Synonyms: Fvw Mesuré/normal
fr-CAFrench (Canada)Protéase clivage du Facteur von Willebrand, Mesuré/normal:Concentration catalytique relative:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:IA
fr-FRFrench (France)Facteur Willebrand protéase patient/témoin:Activité catalytique relative:Ponctuel:Plasma pauvre en plaquettes:Numérique:Immunoanalyse
it-ITItalian (Italy)von Willebrand, proteasi di taglio fattore effettivo/normale:RelCCnc:Pt:PPP:Qn:IA
Synonyms: Concentrazione Catalitica Relativa Fattore di von Willebrand (vWf) Immunoassay Plasma povero di piastrine Proteasi di taglio del fattore di von Willebrand Punto nel tempo (episodio) Studio di coagulazione
nl-NLDutch (Netherlands)von Willebrand-factor cleaving protease gemeten/normaal:relatieve enzymatische activiteit/normaal:moment:plaatjesarm plasma:kwantitatief:immunoassay
Synonyms: coagulatiemethode gemeten/normaal IA
pl-PLPolish (Poland)Proteaza rozkładająca czynnik von Willebranda badane/prawidłowe:względne stężenie katalityczne:punkt w czasie:osocze ubogopłytkowe:ilościowy:metoda immunologiczna
Synonyms: ADAMTS13 Czynnik von Willebranda (vWf) PPP
ru-RURussian (Russian Federation)von Willebrand фактор (vWf) расщепляющая протеаза актуальный/нормальный:ОтнКаталКонц:ТчкВрм:ОПП:Колич:IA
Synonyms: Количественный Обеднённая пластинками плазма;Бедная тромбоцитами плазма Относительная каталитическая концентрация Точка во времени;Момент
tr-TRTurkish (Turkey)von Willebrand faktörü parçalıyıcı proteaz gerçek/normal:GörKtlKons:Zmlı:TFkP:Kant:İA
Synonyms: İmmünölçüm, immünoassay
zh-CNChinese (China)von Willebrand 因子裂解蛋白酶 实际的/正常的:相对催化浓度:时间点:贫血小板血浆:定量型:免疫测定法
Synonyms: von Willebrand von Willebrand 因子（von Willebrand Factor，vWf）;vWf;vWf 因子;血管性假血友病因子;血管性血友病因子 von Willebrand 因子（vWf 因子、血管性假血友病因子、血管性血友病因子）裂解蛋白酶;ADAMTS13;von Willebrand 因子裂解蛋白酶（von Willebrand Factor Cleaving Protease，VWF-cp）;von Willebrand 因子裂解酶;vWCP;vWf 因子裂解蛋白酶;vWf 因子裂解酶;vWf 裂解酶;VWFCP;VWF-cp;血管性血友病因子裂解蛋白酶;血管性血友病因子裂解酶 乏血小板血浆;Platelet poor plasma;PPP 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 冯·威勒布兰德 冯威勒布兰德 冯威勒布兰德氏 凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 因素 实测值 实测值/正常值;实际/正常;实际值/正常值;实际测定值/正常值 实测的 实际值 对照 对照标准 对照物 对照的 时刻;随机;随意;瞬间 朊酶 正常的 系数 蛋白质酵素

Example Units

UnitSource
%Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=97990-6