98064-9

Beta-lactam resistance ESBL blaCTX-M-14 gene [Presence] by Molecular method

Active

Term Description

Qualitative detection of nucleic acids within the beta-lactamase CTX-M-14 gene (blaCTX-M-14) found in Gram-negative bacteria. Testing may be performed in addition to conventional culture susceptibility testing to determine the potential bacterial resistance mechanism to antibiotics.
Source: Regenstrief LOINC

Part Description

LP426519-7 Bacterial beta-lactam resistance ESBL blaCTX-M-14 gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some bacteria that are resistant to the majority of beta-lactam antibiotics which include the penicillins, cephalosporins and the monobactam aztreonam. [https://www.uptodate.com/contents/extended-spectrum-beta-lactamases] Organisms producing CTX-M type ESBL enzymes have been isolated worldwide with more than 150 enzymes identified. These enzymes have been classified into seven major phylogenetic groups: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25, CTX-M-74 and CTX-M-75. CTX-M-9 group includes CTX-M-14 and CTX-M-15. The rare ESBL type CTX-M-8 has been isolated in Germany, mainly in E. coli, but also in Salmonella and E. aerogenes. CTX-M type ESBL have been isolated worldwide and their incidence has increased dramatically and is still increasing leading to a major therapeutic issue. Currently more than 150 allelic variants of CTX-M have been identified. The dissemination of these enzymes has caused an increased use of carbapenems for treatment of infections which carries its own risk of furthering resistance. PMID: 25234380 The genes are named with the prefix "bla", which stands for "beta-lactam", followed by the enzyme, for example, blaCTX-M-1. Source: LOINC

Fully-Specified Name

Component: Bacterial beta-lactam resistance ESBL blaCTX-M-14 gene
Property: PrThr
Time: Pt
System: Isolate/Specimen
Scale: Ord
Method: Molgen

Additional Names

Short Name: ESBL blaCTX-M-14 gene Islt/Spm Ql
Display Name: Beta-lactam resistance ESBL blaCTX-M-14 gene Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info: Beta-lactam resistance ESBL blaCTX-M-14 gene

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.70
Last Updated: Version 2.72
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Bakterielle Beta-Lactam-Resistenz ESBL blaCTX-M-14-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch Synonyms: Extended Spectrum beta-lactamases
es-ES	Spanish (Spain)	gen bacteriano ESBL blaCTX-M-14 resistente a betalactámicos:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MX	Spanish (Mexico)	Resistencia bacteriana a betalactámicos BLEE gen blaCTX-M-14:PrThr:Punto temporal:Aislar / Muestra:Ordinal:Molgen
fr-FR	French (France)	Résistance bactérienne aux bêta lactamases ESBL blaCTX-M-14 gène:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-IT	Italian (Italy)	Resistenza batterica beta-lactamica, gene ESBL blaCTX-M-1:PrThr:Pt:Isolato/Campione:Ord:Molgen Synonyms: Gene ESBL blaCTX-M-1 di resistenza batterica beta-lactamica Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NL	Dutch (Netherlands)	bacteriële bètalactamresistentie ESBL blaCTX-M-14-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek Synonyms: isolaat/specimen molgen
zh-CN	Chinese (China)	细菌 beta-内酰胺耐药 ESBL blaCTX-M-14 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法 Synonyms: B M 型 β 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分离株/标本（样本、样品、试样）分离物;分离菌;分离菌株;隔离种群受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）抗力抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类抗耐性抵抗力抵抗性时刻;随机;随意;瞬间样品样本电阻细菌 beta-内酰胺（β-内酰胺）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） ESBL（超广谱β-内酰胺酶） blaCTX-M-14 基因细菌性细菌的耐性试样贝塔遗传基因;遗传因子;吉恩;生物基因阻力

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