98081-3

Cytomegalovirus DNA [#/volume] (viral load) in Saliva (oral fluid) by NAA with probe detection

Active

Part Descriptions

LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html Source: Regenstrief LOINC

LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Cytomegalovirus DNA:NCnc:Pt:Saliva:Qn:Probe.amp.tar
Long Common Name: Cytomegalovirus DNA [#/volume] (viral load) in Saliva (oral fluid) by NAA with probe detection
Short Name: CMV DNA # Sal NAA+probe
Display Name: CMV DNA NAA+probe (Sal) [#/Vol]
Consumer Name Alpha Get Info: Cytomegalovirus (CMV), Saliva

Part Model Get Info

Component
Cytomegalovirus DNA
LP37883-3
- Analyte
  Cytomegalovirus DNA
  LP37883-3
  - Component Numerator
    Cytomegalovirus DNA
    LP37883-3
    - Component Numerator Core
      Cytomegalovirus
      LP14255-1
    - Component Numerator Core Suffix
      DNA
      LP32416-7
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NCnc
LP6836-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Saliva
LP7565-7
- System Core
  Saliva
  LP7565-7
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Probe.amp.tar
LP6464-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.71
Last Updated: Version 2.71 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cytomegalovirus DNA:Početní koncentrace:Časový bod:Sliny:Kvantitativní:Amplifikace nukleových kyselin s detekcí sondou
de-DE	German (Germany)	Cytomegalie-Virus DNA:Anzahl pro Volumen:Zeitpunkt:Speichel:Quantitativ:Zielfragmentamplifikation mit Sondendetektion Synonyms: CMV
el-GR	Greek (Greece)	Κυτταρομεγαλοϊός DNA:NCnc:Pt:Σίελος:Qn:Ανιχνευτής.ενίσχυση.στόχου Synonyms: DNA MICRO NCnc Pt Qn Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Κυτταρομεγαλοϊός Σίελος
es-ES	Spanish (Spain)	Citomegalovirus ADN:Concentración de número:Punto temporal:Saliva:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo
fr-CA	French (Canada)	Cytomégalovirus, ADN:Concentration numérique:Temps ponctuel:Salivaire:Quantitatif:Sonde avec amplification de la cible
fr-BE	French (Belgium)	Cytomégalovirus ADN:Concentration numérique:Temps ponctuel:Salivaire:Quantitatif:Sonde avec amplification de la cible Synonyms: CMV
fr-FR	French (France)	Cytomégalovirus ADN:Nombre/Volume:Ponctuel:Salive:Numérique:PCR amplification de cible
it-IT	Italian (Italy)	Citomegalovirus DNA:NCnc:Pt:Saliva:Qn:Sonda.amp.tar Synonyms: Concentrazione Numerica Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Cytomegalovirus DNA:aantal/volume:moment:speeksel:kwantitatief:probe-detectie Synonyms: probe.amp.tar
pl-PL	Polish (Poland)	Wirus cytomegalii DNA:stężenie liczbowe:punkt w czasie:ślina:ilościowy:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Cytomegalowirus DNA Cytomeglaowirusa koncentracja Kwas deoksyrybonukleinowy
ru-RU	Russian (Russian Federation)	Цитомегаловирус ДНК:КолОб:ТчкВрм:Слюна:Колич:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Количественный Количество в объеме Проба с мишени усилением Точка во времени;Момент
tr-TR	Turkish (Turkey)	Cytomegalovirus DNA:SayKons:Zmlı:Tükürük:Kant:Prob.amf.hdf
zh-CN	Chinese (China)	巨细胞病毒 DNA:计数型浓度:时间点:唾液:定量型:探针法.基因扩增.靶向 Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向单位体积内的数量或计数;数量型浓度(单位体积);数量或计数型浓度(计数/体积);数量或计数型浓度(单位体积);计数型浓度(单位体积) 去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性数量型浓度探针法.基因扩增.靶向数量型浓度探针法.扩增.靶向数量或计数型浓度探针法.扩增.靶向时刻;随机;随意;瞬间津;津液;涎病毒负荷病毒负荷量病毒负载病毒载量病毒载量（Viral load）经过扩增的脱氧核糖核酸探针计数型浓度探针法.基因扩增.靶向计数型浓度探针法.扩增.靶向

Example Units

Unit	Source
{copies}/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.