Version 2.78

Term Description

Identifies an evening specimen when cortisol is at its lowest point in a circadian cycle -often considered to be midnight. Some laboratories will call this "12AM (midnight)" specimen, but specimens in the range of 11PM to 1AM are acceptable. The trough time may have to be adjusted for patients on different work shifts because their circadian rhythms can shift with their sleeping time.
Source: Regenstrief LOINC

Part Descriptions

LP14161-1   Cortisol
Cortisol is a glucocorticoid produced in the adrenal cortex. A synthetic version of this same chemical is called hydrocortisone and manufactured as medication. Cortisol is not to be confused with cortisone, a closely related compound with much less (PubChem calls it "inactive") biologic activity. Cortisone is also offered as a drug, and it is converted to cortisol (the active form) in the liver. They both have a circadian rhythm with peak in the AM (around 8AM) and trough in the evening (around midnight), but this shifts according to sleep habits (work shifts). The morning measurement, which should be high, is most useful for diagnosing Addison's disease (too little cortisol) and the evening measurement, which should be low, is the most useful for diagnosing Cushing's disease (too much cortisol). Salivary cortisol may be a more sensitive measure than serum or plasma. Source: Regenstrief Help

LP156504-5   PM trough specimen
Identifies an evening specimen when analyte is at its lowest point in a circadian cycle -often considered to be midnight. Some laboratories will call this "12AM (midnight)" specimen, but specimens in the range of 11PM to 1AM are acceptable. The trough time may have to be adjusted for patients on different work shifts because their circadian rhythms can shift with their sleeping time. Source: Regenstrief Help

Fully-Specified Name

Component
Cortisol^PM trough specimen
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Cortis PM SerPl-mCnc
Display Name
Cortisol PM trough specimen [Mass/Vol]
Consumer Name Alpha Get Info
Cortisol PM Trough specimen, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 1.0i
Last Updated
Version 2.73
Change Reason
To avoid two ways (PM and evening) of saying the same thing. We chose PM because it is shorter. 'Trough' clarifies that specimen is collected when cortisol is expected to be at the lowest level.
Order vs. Observation
Both
Common Test Rank Get Info
2939

Member of these Panels

LOINC Long Common Name
87429-7 Cortisol AM and PM panel - Serum or Plasma
100662-6 Cortisol free and total panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group Group Name
LG50773-7 Cortisol^PM trough specimen|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cortisol^Nachmittag-Talspiegel-Probenmaterial:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
Synonyms: Kortisol
es-AR Spanish (Argentina) cortisol^vespertino:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Cortisol^PM muestra valle:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Cortisol ^ PM a través de la muestra:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CA French (Canada) Cortisol^Spécimen creux PM:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Cortisol résiduel Soir:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Cortisol^Spécimen PM minimal:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Echantillon. PM.minimal Minimum, nadir
it-IT Italian (Italy) Cortisolo^campione minimo serale:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
ko-KR Korean (Korea, Republic Of) 코티솔^저녁:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) cortisol^middag-dalspiegelmonster:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Cortisol^amostra noturna:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; Cortis; Coritsol; Compound F; 17-Hydroxycorticosterone; PM; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Spec; Chemistry
ru-RU Russian (Russian Federation) Кортизол^Вечерний минимальный образец:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Провал концетрации кортизола наблюдающийся с 23:00 до 1:00 Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Kortizol^Öğleden sonra örneği:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
uk-UA Ukrainian (Ukraine) Кортизол^вечірній мінімальний зразок:Масова Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:
Synonyms: 12 AM; 12AM; 17-Hydroxycorticosterone; Chemistry; circadian low; Compound F; Coritsol; Cort; Evening; F; hydrocortisone; late night specimen; Level; Mass concentration; Midnight; Pl; Plasma; Plsm; PM diurnal trough; Point in time; Pre; Predose; Pre-dose; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; Spec; SR; UniversalLabOrders
zh-CN Chinese (China) 皮质醇^晚上波谷标本:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 17-羟皮质甾酮;17-羟皮质酮;化合物 F;可的索;氢化可的松;皮质甾醇;考的索 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 受检物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 晚上（晚间）波谷（谷值、低谷、最小值、最低点）标本（样本、样品、试样） 样品 样本 水平;浓度;质量浓度(单位体积) 血清或血浆 试样

Example Units

Unit Source
mcg/dL REGENSTRIEF
ug/dL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=9812-9