Version 2.77

Part Description

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Coronavirus (COVID-19) Testing

Fully-Specified Name

Component
SARS coronavirus 2 spike protein RBD Ab.neut
Property
ACnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
IA

Additional Names

Short Name
SARS-CoV-2 S RBD NAb SerPl IA-aCnc
Display Name
SARS-CoV-2 (COVID-19) S protein RBD neut ab IA Qn
Consumer Name Alpha Get Info
SARS-CoV-2 (COVID-19) S protein RBD neutralizing antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.72
Last Updated
Version 2.72
Order vs. Observation
Observation

Member of these Groups Get Info

LOINC Group Group Name
LG51018-6 SARSCoV2 antibody detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) SARS Coronavirus 2-Spike-Protein RBD Ak.neutralisierend:Arbiträre Konzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:Immunoassay
es-ES Spanish (Spain) Dominio de unión al recepto r(RBD) de la proteína de la espícula del SARS-CoV-2 (COVID-19) Anticuerpos antineutrófilos:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA
Synonyms: Cuantitativo
fr-FR French (France) Coronavirus SARS-CoV-2 protéine spike RDB Ac neutralisant:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
it-IT Italian (Italy) SARS coronavirus 2, proteina spike RBD Ab.Neut:ACnc:Pt:Siero/Plasma:Qn:IA
Synonyms: anticorpo Concentrazione Arbitraria Coronavirus della SARS Immunoassay Microbiologia Plasma Proteina spike di SARS-CoV-2 (COVID-19) Proteina spike dominio che lega il recettore (RBD) di SARS Cov-2 (COVID-19) Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Siero Siero o Plasma
nl-NL Dutch (Netherlands) SARS-CoV-2 'spike'-eiwit RBD As.neutraliserend:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19
pl-PL Polish (Poland) Domena RBD białka S SARS-CoV-2 Ab.Neutralizujące:stężenie w jednostkach umownych:punkt w czasie:surowica lub osocze:ilościowy:metoda immunologiczna
Synonyms: Koronawirus Przeciwciała neutralizujące do domeny wiążącej receptor białka kolca S wirusa SARS-CoV-2 (COVID-19)
zh-CN Chinese (China) SARS 冠状病毒 2 刺突蛋白 RBD 抗体.中和:任意型浓度:时间点:血清/血浆:定量型:免疫测定法
Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ Ab;自身抗体 II PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 SARS 冠状病毒 2 刺突蛋白(棘突蛋白、棘刺蛋白) RBD;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 SARS 冠状病毒 2 刺突蛋白(棘突蛋白、棘刺蛋白);2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒 中和试验;中和抗体;中和 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 时刻;随机;随意;瞬间 血清或血浆

Example Units

Unit Source
[IU]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=98734-7