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Description

The ACSL4 gene (acyl-CoA synthetase long-chain family member 4) [HGNC Gene ID:3571] is located on chromosome Xq22.3-q23. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] [NCBI Gene ID:2182] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Name
ACSL4 gene
Part Display Name
ACSL4 gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2010-09-13
Construct for LOINC Short Name
ACSL4 gene

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Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)ACSL4 基因
Synonyms: ACS4;FACL4;LACS4;MRX63;MRX68;acyl-CoA synthetase long-chain family member 4;乙酰辅酶A合成酶长链家族成员4;智力低下, X 连锁非特异性, 63;Mental retardation, X-linked non-specific, 63
et-EEEstonian (Estonia)ACSL4 geen
es-ESSpanish (Spain)Gen ACSL4
it-ITItalian (Italy)ACSL4, gene
Synonyms: Gene ACSL4
tr-TRTurkish (Turkey)ACSL4 geni
ru-RURussian (Russian Federation)ACSL4 ген
nl-NLDutch (Netherlands)ACSL4-gen
Synonyms: ACSL4 gen
fr-FRFrench (France)ACSL4 gène
pl-PLPolish (Poland)ACSL4 gen
Synonyms: Gen ACSL4
el-GRGreek (Greece)Γονίδιο ACSL4
Synonyms: Γονίδιο ACSL4