Version 2.77

Description

The presence of antibodies to gliadin peptide and tissue transglutaminase can be used in conjunction with clinical findings and other lab tests to aid in the diagnosis of IgA sufficient and IgA deficient celiac disease.

Antibodies to deamidated gliadin peptide and tissue transglutaminase are specific to Celiac Disease while antibodies to gliadin are present in patients with and without gastrointestinal manifestations and are serological evidence of gluten sensitivity.

The screening starts with testing for IgA and IgG antibodies to deamidated gliadin peptide (DGP) and tissue transglutaminase (tTG) that allows for simultaneous detection for all four types of antibodies in one test (tTG/DGP screen). This step will aid in the diagnosis of gluten-sensitive enteropathies including celiac disease. Antibodies to DGP and tTG are highly specific and sensitive for those conditions When the result is positive, testing stops. When result is negative, testing will reflex to a second step. Source: LOINC partner 1

Basic Part Properties

Part Display Name
Gliadin peptide+tissue transglutaminase
Part Type
Component (Describes the core component or analyte measured)
Created On
2011-01-27
Construct for LOINC Short Name
Gliadin peptide+tTG

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP113725-8

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 麦醇溶蛋白肽+组织谷氨酰胺转移酶
Synonyms: 醇溶朊肽;醇溶蛋白肽;麦胶蛋白肽;麸朊肽;麸蛋白肽;麦醇溶蛋白肽+组织转谷氨酰胺酶
fr-CA French (Canada) Toxine 1 du syndrôme du choc toxique de Staphylococcus aureus
et-EE Estonian (Estonia) Gliadiin + koe transglutaminaas
es-ES Spanish (Spain) Gliadina+transglutaminasa tisular
it-IT Italian (Italy) Peptide della gliadina+Transglutaminasi tissutale
tr-TR Turkish (Turkey) Gliadin peptid+doku transglutaminaz
ru-RU Russian (Russian Federation) Глиадин пептид+тканевая трансглутаминаза
nl-NL Dutch (Netherlands) gliadinepeptide + tissue transglutaminase
fr-BE French (Belgium) Gliadine peptidique+Transglutaminase de tissu
pl-PL Polish (Poland) Peptyd gliadyny+transglutaminaza tkankowa
Synonyms: Peptyd gliadyny i transglutaminaza tkankowa