Description

Excision repair cross-complementation group 1 (ERCC1) is required for nucleotide excision repair of damaged DNA and is homologous to RAD10. In mammalian cells, XPG cleaves 3' of the DNA lesion while ERCC1-XPF complex makes the 5' incision. In patients with non-small cell lung cancer (NSCLC), studies have shown that levels of expression of ERCC1 in tumors are indicative of treatment outcome for various types of chemotherapy. Source: LOINC partner 1

Basic Part Properties

Part Name
ERCC1
Part Display Name
ERCC1
Part Type
Component (Describes the core component or analyte measured)
Created On
2011-11-30
Construct for LOINC Short Name
ERCC1

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP140220-7

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)ERCC1
Synonyms: Excision repair cross-complementation group 1;核苷酸切除修复交叉互补组 1;核苷酸切除修复交叉互补组基因蛋白 1;切除修复交叉互补基因 1
es-ESSpanish (Spain)ERCC1 (proteína de reparación por escisión del grupo de complementación cruzada 1)
it-ITItalian (Italy)ERCC1
tr-TRTurkish (Turkey)ERCC1
ru-RURussian (Russian Federation)ERCC1
nl-NLDutch (Netherlands)ERCC1
fr-FRFrench (France)ERCC1
el-GRGreek (Greece)ERCC1
Synonyms: ERCC1