LP14037-3

Plasma cells

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Descriptions

Plasma cells (or plasmocytes) are cells of the immune system that secrete large amounts of antibodies. They differentiate from B cells upon stimulation by antigen-activated CD4+ lymphocytes (or T lymphocytes) . They are found in the medulla of the lymph node, in the bone marrow and in the red pulp of the spleen. The differentiation of B cells into plasma cells is accompanied by many morphological changes that allow the cell to synthesize and secrete large amounts of antibodies. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Plasma cells (Wikipedia)

Specialized forms of antibody-producing B-lymphocytes. They synthesize and secrete immunoglobulin. They are found only in lymphoid organs and at sites of immune responses and normally do not circulate in the blood or lymph. (Rosen et al., Dictionary of Immunology, 1989, p169 & Abbas et al., Cellular and Molecular Immunology, 2d ed, p20) Source: National Library of Medicine, MeSH 2006

Basic Part Properties

Part Display Name

Plasma cells

Part Type

Component (Describes the core component or analyte measured)

Created On

2000-05-04

Construct for LOINC Short Name

Plasma Cells

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