LP145765-6
SERPINC1 gene
Active
Description
The SERPINC1 gene (serpin peptidase inhibitor, clade C (antithrombin), member 1) [HGNC Gene ID:775] is located on chromosome 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq, Jul 2009] [NCBI Gene ID:462] Source: National Center for Biotechnology Information (NCBI) Gene
Basic Part Properties
- Part Name
- SERPINC1 gene
- Part Display Name
- SERPINC1 gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2012-01-23
- Construct for LOINC Short Name
- SERPINC1 gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | SERPINC1 基因 Synonyms: AT3; |
| es-ES | Spanish (Spain) | Gen SERPINC1 |
| it-IT | Italian (Italy) | SERPINC1, gene Synonyms: Gene SERPINC1 |
| tr-TR | Turkish (Turkey) | SERPINC1 geni |
| ru-RU | Russian (Russian Federation) | SERPINC1 ген |
| nl-NL | Dutch (Netherlands) | SERPINC1-gen Synonyms: SERPINC1 gen |
| fr-FR | French (France) | SERPINC1 gène |
| pl-PL | Polish (Poland) | SERPINC1 gen Synonyms: Gen SERPINC1 |
| el-GR | Greek (Greece) | Γονίδιο SERPINC1 Synonyms: Γονίδιο SERPINC1 |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://