Version 2.77

Description

Plasmodium knowlesi is a primate malaria parasite commonly found in Southeast Asia. It causes malaria in long-tailed macaques (Macaca fascicularis), but it may also infect humans, either naturally or artificially.

Plasmodium knowlesi is the fifth major human malaria parasite. It may cause severe malaria as indicated by its asexual erythrocytic cycle of about 24 hours, with an associated fever that typically occurs at the same frequency (i.e. the fever is quotidian). This is an emerging infection that was reported for the first time in humans in 1965. It accounts for up to 70% of malaria cases in certain areas in South East Asia where it is mostly found. This parasite is transmitted by the bite of an Anopheles mosquito. Plasmodium knowlesi has health, social and economic consequences for the regions affected by it.

Although the current infection rate with Plasmodium knowlesi is relatively low, one risk it presents is misdiagnosis with other forms of malarial parasites such as P. malariae especially when microscopy is used. P. knowlesi can only be accurately distinguished from P. malariae using PCR assay and/or molecular characterization.

Because P. knowlesi takes only 24 hours to complete its erythrocytic cycle, it can result in very high parasite density quickly and may be fatal in humans. For this reason early treatment is advised. It responds well to treatment with chloroquine and primaquine. but if parasite counts are high and patients are severe, then infections should be treated as intensively as for severe falcipaum malaria. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Basic Part Properties

Part Display Name
Plasmodium knowlesi
Part Type
Component (Describes the core component or analyte measured)
Created On
2012-03-06
Construct for LOINC Short Name
P knowlesi

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP146623-6
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP146623-6

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 诺氏疟原虫
Synonyms: 诺耳斯氏疟原虫;诺氏疟原虫（猴）
es-ES Spanish (Spain) Plasmodium knowlesi
it-IT Italian (Italy) Plasmodium knowlesi
tr-TR Turkish (Turkey) Plasmodium knowlesi
ru-RU Russian (Russian Federation) Plasmodium knowlesi
nl-NL Dutch (Netherlands) Plasmodium knowlesi