Version 2.80

Descriptions

The C1 esterase inhibitor assay is used to diagnose hereditary angioneurotic edema. Exhaustion of C1 esterase inhibitor allows spontaneous auto-catalytic C1 activation and the break down of C2 and C components. The disease can be caused by low concentrations or the abnormal structure of the protein. The disease is inherited as an autosomal dominant trait and has been successfully treated with prednisolone and transfusion of fresh frozen plasma. Source: Regenstrief Institute

In congenital form of angioedema there is a deficiency in C-1 esterase inhibitor detectable by nephelometry. Acquired forms are usually associated with qualitative (functional) deficiency of the inhibitor. This is best detected by the enzyme immunoassay for the functional component. To detect acquired forms of angioedema due to deficency of C-1 esterase inhibitor (C1-INH), a multispecific, protease inhibitor that is present in normal human plasma is measured. Source: Regenstrief Institute

Basic Part Properties

Part Name
Complement C1 esterase inhibitor
Part Display Name
Complement C1 esterase inhibitor
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
C1INH

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14797-2

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 补体 C1 酯酶抑制剂
Synonyms: C1 抑制因子;C1 灭活剂;C1 灭活因子;C1INA;C1INH;C1-INH;补体 C1 酯酶抑制因子
es-ES Spanish (Spain) Complemento inhibidor de C1 esterasa.
it-IT Italian (Italy) Complemento C1 esterasi inibitore
et-EE Estonian (Estonia) Komplemendi komponendi C1 inhibiitor
tr-TR Turkish (Turkey) Kompleman C1 esteraz inhibitör
ru-RU Russian (Russian Federation) Комплемента С1 эстеразы ингибитор
fr-BE French (Belgium) Inhibiteur de la C1 estérase
fr-CA French (Canada) Inhibiteur de la C1 estérase
nl-NL Dutch (Netherlands) complement C1-esteraseremmer
el-GR Greek (Greece) Αναστολέας εστεράσης συμπληρώματος C1
Synonyms: Αναστολέας εστεράσης συμπληρώματος C1