Description

Rotaviruses cause significant gastrointestinal disease, primarily in children under 5 years old. Rotaviruses comprise a genus within the family Reoviridae with nine existing groups. Groups A, B and C (RVA, RVB and RVC) infect humans while all existing groups can infect animals. RV causes diarrhea by destroying the enterocytes in the small intestine. Recent studies confirm that rotavirus infection can also extend beyond the intestine. Examples of extraintestinal infection include the findings of the virus in the liver during autopsy, elevated liver enzymes during active infection and the demonstration of the virus replicating both in the liver and kidneys of a child suffering from immunodeficiency. PMID: 15367586
Rotaviruses (RVs) also cause severe diarrhea in animals. Research has revealed that pigs can suffer both single and mixed concurrent infections with more than one Rotavirus group. In one study, pigs that had been vaccinated against one strain of RVA were still part of a diarrhea outbreak later and found to have both single and mixed infections that included RVB, RVC and RVH as well as RVA strains that were not part of the vaccine. This suggests that diagnostic testing for multiple RV groups should be included when testing a swine herd for enteric diseases even after they have been vaccinated against a single strain.
PMID: 27599939 Source: Regenstrief LOINC

Basic Part Properties

Part Name
Rotavirus
Part Display Name
Rotavirus
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
RV

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Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)轮状病毒
Synonyms: ROTAV;RV
fr-CAFrench (Canada)Rotavirus
et-EEEstonian (Estonia)Rotaviirus
es-ESSpanish (Spain)Rotavirus
it-ITItalian (Italy)Rotavirus
tr-TRTurkish (Turkey)Rotavirus
ru-RURussian (Russian Federation)Ротавирус
nl-NLDutch (Netherlands)Rotavirus
fr-BEFrench (Belgium)Rotavirus
fr-FRFrench (France)Rotavirus
pl-PLPolish (Poland)Rotawirus
el-GRGreek (Greece)Ροταϊός
Synonyms: Ροταϊός