LP14903-6
Basement membrane
Active
Descriptions
The basement membrane is a thin sheet of fibers that underlies the epithelium, which lines the cavities and surfaces of organs including skin, or the endothelium, which lines the interior surface of blood vessels.
The primary function of the basement membrane is to anchor down the epithelium to its loose connective tissue underneath. This is achieved by cell-matrix adhesions through substrate adhesion molecules. A group of diseases stemming from improper function of basement membrane zone are united under the name epidermolysis bullosa.
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Source: Wikipedia, Basement membrane (Wikipedia)
A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers. Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Display Name
- Basement membrane
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- BM
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 基底膜 Synonyms: Goodpastures样综合征; |
| fr-CA | French (Canada) | Membrane basale |
| et-EE | Estonian (Estonia) | Basaalmembraani vastased |
| es-ES | Spanish (Spain) | Membrana basal |
| it-IT | Italian (Italy) | Membrana basale |
| tr-TR | Turkish (Turkey) | Bazal membran Synonyms: Temel membran; |
| ru-RU | Russian (Russian Federation) | Базальная мембрана |
| nl-NL | Dutch (Netherlands) | basaalmembraan |
| fr-BE | French (Belgium) | Membrane basale |
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