LP149676-1
Mycobacterium tuberculosis stimulated gamma interferon
Active
Description
Interferon-γ (interferon-gamma) release assays (IGRAs) are based on the ability of the Mycobacterium tuberculosis antigens for early secretory antigen target 6 (ESAT-6) and culture filtrate protein 10 (CFP-10) to stimulate host production of interferon-gamma. Because these antigens are not present in non-tuberculous mycobacteria or in any BCG vaccine variant, these tests can distinguish latent tuberculosis infection (LTBI). The blood tests QuantiFERON-TB Gold In-Tube and T-SPOT.TB use these antigens to detect people with tuberculosis. Lymphocytes from the patient's blood are incubated with the antigens. If the patient has been exposed to tuberculosis before, T lymphocytes produce interferon γ in response. These tests are both interferon γ tests but they are not equivalent. The QuantiFERON-TB Gold In-Tube uses an ELISA format to quantify the total amount of interferon γ when whole blood is exposed to the antigens (ESAT-6,CFP-10 and TB 7.7). T-SPOT.TB is a type of enzyme-linked immunospot assay (ELISPOT) assay, which counts the number of activated T lymphocytes that secrete interferon γ. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia
Basic Part Properties
- Part Display Name
- Mycobacterium tuberculosis stimulated gamma interferon
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2012-04-06
- Construct for LOINC Short Name
- M TB IFN-g
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 结核分枝杆菌刺激型 gamma 干扰素 Synonyms: 结核分枝杆菌刺激型 gamma 干扰素（γ干扰素、 |
| fr-CA | French (Canada) | Mycobacterium tuberculosis, stimulation par le gamma Interféron |
| es-ES | Spanish (Spain) | Mycobacterium tuberculosis estimulado con interferón gamma |
| it-IT | Italian (Italy) | Mycobacterium tuberculosis, gamma interferone stimolato Synonyms: Gamma interferone stimolato da Mycobacterium tuber |
| tr-TR | Turkish (Turkey) | Mycobacterium tuberculosis indüklenmiş gamma interferon |
| ru-RU | Russian (Russian Federation) | Mycobacterium tuberculosis стимулированный гамма интерферон |
| nl-NL | Dutch (Netherlands) | Mycobacterium tuberculosis gestimuleerd gamma-interferon |
| fr-BE | French (Belgium) | Mycobacterium tuberculosis, stimulation par gamma Interféron |
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