LP15152-9
Corticotropin releasing hormone
Active
Description
Corticotropin-releasing hormone (CRH), originally named corticotropin-releasing factor (CRF), and also called corticoliberin, is a polypeptide hormone and neurotransmitter involved in the stress response.
Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in CRH has been observed in association with Alzheimer's disease, and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially-fatal metabolic consequences including hypoglycemia and hepatitis. In addition to being produced in the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta, CRH is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, CRH may act as a trigger for parturition.
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Source: Wikipedia, Corticotropin releasing hormone
Basic Part Properties
- Part Display Name
- Corticotropin releasing hormone
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- ACTH RH
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 促肾上腺皮质激素释放激素 Synonyms: ACTH RH; |
| fr-CA | French (Canada) | Hormone de libération de la CRH |
| et-EE | Estonian (Estonia) | Kortikotropiini vabastav hormoon |
| es-ES | Spanish (Spain) | Hormona liberadora de Corticotropina |
| it-IT | Italian (Italy) | Ormone rilasciante corticotropina |
| tr-TR | Turkish (Turkey) | Kortikotropin salıcı hormon |
| ru-RU | Russian (Russian Federation) | Кортикотропин-высвобождающий гормон Synonyms: Кортикотропин-высвобождающий фактор; |
| nl-NL | Dutch (Netherlands) | ACTH-releasing hormoon Synonyms: corticotrofine-''releasing'' hormoon; |
| fr-BE | French (Belgium) | Hormone de libération de l'ACTH Synonyms: ACTH-RF, ACTH-releasing factor |
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