LP15160-2
Pyruvate kinase
Active
Descriptions
ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the presence of ATP. It has four isozymes (L, R, M1, and M2). Deficiency of the enzyme results in hemolytic anemia. EC 2.7.1.40. Source: National Library of Medicine, MeSH 2006
Pyruvate Kinase deficiency, although rare, is the erythrocyte enzyme deficiency most frequently found to be a cause of congenital nonspherocytic hemolytic anemia. Patients usually present early in childhood with anemia, icterus, and splenomegaly. Hemolytic disease of the newborn is common in persons with PK deficiency. Source: Regenstrief Institute
Basic Part Properties
- Part Display Name
- Pyruvate kinase
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- PK
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 丙酮酸激酶 Synonyms: PK |
| fr-CA | French (Canada) | Pyruvate kinase |
| et-EE | Estonian (Estonia) | Püruvaadi kinaas |
| es-ES | Spanish (Spain) | Piruvato quinasa |
| it-IT | Italian (Italy) | Piruvato chinasi |
| tr-TR | Turkish (Turkey) | Piruvat kinaz |
| ru-RU | Russian (Russian Federation) | Пируваткиназа |
| nl-NL | Dutch (Netherlands) | pyruvaatkinase |
| fr-BE | French (Belgium) | Pyruvate kinase |
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