LP15173-5
Mercaptopurine
Active
Descriptions
Mercaptopurine, a cancer fighting medicine, which also can be used to treat many types of autoimmune disease, such as systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis. It belongs to a group of drugs known as antimetabolites; cancer cells take up mercaptopurine which then interferes with their growth. Source: Regenstrief Institute
6-Mercaptopurine (6-MP) is used in treatment of inflammatory bowel disease. The effects of 6-mercaptopurine (6-MP) are mediated via its intracellular conversion (RBC) to 6-thioguanine (6-TG) and 6-methylmercaptopurine (6-MMP) nucleotide metabolites, the latter genetically controlled by thipurine methyltransferase (TPMT). This assay measures level of 6-MMP which has been shown to correlate with therapeutic response and potential toxicities. Source: Regenstrief Institute
Mercaptopurine (also called 6-mercaptopurine, 6-MP or its brand name Purinethol) is an immunosuppressive drug.
It is used to treat leukemia, pediatric non-Hodgkin's lymphoma, polycythemia vera,psoriatic arthritis, and inflammatory bowel disease such as Crohn's disease and ulcerative colitis.
It has demonstrated some in vitro effectiveness against Mycobacterium paratuberculosis.
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Source: Wikipedia, Wikipedia
Basic Part Properties
- Part Display Name
- Mercaptopurine
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Mercaptopurine
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 6-巯基嘌呤 Synonyms: 乐疾宁; |
| fr-CA | French (Canada) | Mercaptopurine |
| et-EE | Estonian (Estonia) | Merkaptopuriin |
| es-ES | Spanish (Spain) | Mercaptopurina |
| it-IT | Italian (Italy) | Mercaptopurina |
| tr-TR | Turkish (Turkey) | merkaptopürin |
| ru-RU | Russian (Russian Federation) | Меркаптопурин |
| nl-NL | Dutch (Netherlands) | mercaptopurine |
| fr-BE | French (Belgium) | Mercaptopurine |
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