Description

In enzymology, a methylenetetrahydrofolate reductase (ferredoxin) (EC 1.5.7.1) is an enzyme that catalyzes the chemical reaction

5-methyltetrahydrofolate + 2 oxidized ferredoxin 5,10-methylenetetrahydrofolate + 2 reduced ferredoxin + 2 H+
Thus, the two substrates of this enzyme are 5-methyltetrahydrofolate and oxidized ferredoxin, whereas its 3 products are 5,10-methylenetetrahydrofolate, reduced ferredoxin, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is 5-methyltetrahydrofolate:ferredoxin oxidoreductase. This enzyme is also called 5,10-methylenetetrahydrofolate reductase. This enzyme participates in one carbon pool by folate. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Basic Part Properties

Part Name
5,10-Methylenetetrahydrofolate reductase
Part Display Name
5,10-Methylenetetrahydrofolate reductase
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
MTHFR

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15306-1

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)5,10-亚甲基四氢叶酸还原酶
Synonyms: FADH2;MTHFR
fr-CAFrench (Canada)5,10-méthylènetétrahydrofolate réductase
et-EEEstonian (Estonia)5,10-metüleentetrahüdrofolaadi reduktaas
es-ESSpanish (Spain)5,10-Metilenetetrahidrofolato reductasa
it-ITItalian (Italy)5,10-Metilenetetraidrofolato reduttasi
tr-TRTurkish (Turkey)5,10-Metilentetrahidrofolat reduktaz
ru-RURussian (Russian Federation)5,10-Метилентетрагидрофолат редуктаза
nl-NLDutch (Netherlands)5,10-methyleentetrahydrofolaatreductase
fr-BEFrench (Belgium)5,10-méthylènetétrahydrofolate réductase
Synonyms: MTHFR
fr-FRFrench (France)5,10-méthylènetétrahydrofolate réductase
el-GRGreek (Greece)Αναγωγάση του 5,10 - µεθυλενοτετραϋδροφυλλικού
Synonyms: Αναγωγάση του 5,10 - µεθυλενοτετραϋδροφυλλικού