LP15319-4
Acyl CoA dehydrogenase
Active
Description
Acyl-CoA dehydrogenases are a class of enzymes that function to catalyze the initial step in each cycle of fatty acid β -oxidation in the mitochondria of cells. Their action results in the introduction of a trans double-bond between C2 and C3 of the acyl-CoA thioester substrate. FAD is a required co-factor in the mechanism in order for the enzyme to bind to its appropriate substrate. Acyl-CoA dehydrogenases can be categorized into three distinct groups based on their specificity for short-, medium-, or long-chain fatty acid acyl-CoA substrates. While different dehydrogenases target fatty acids of varying chain length, all types of acyl-CoA dehydrogenases are mechanistically similar. Differences in the enzyme occur based on the location of the active site along the amino acid sequence. Acyl-CoA dehydrogenases are an important class of enzymes in mammalian cells because of their role in metabolizing fatty acids present in ingested food materials. This enzyme's action represents the first step in fatty acid metabolism (the process of breaking long chains of fatty acids into acetyl CoA molecules). Deficiencies in these enzymes are linked to genetic disorders involving fatty acid oxidation (i.e. metabolic disorders). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Acyl-CoA dehydrogenase
Basic Part Properties
- Part Name
- Acyl CoA dehydrogenase
- Part Display Name
- Acyl CoA dehydrogenase
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- ACAD
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 酰基 CoA 脱氢酶 Synonyms: AcdA; |
| es-ES | Spanish (Spain) | Acil Coenzima A deshidrogenasa |
| it-IT | Italian (Italy) | Acil CoA deidrogenasi |
| tr-TR | Turkish (Turkey) | Açil KoA dehidrojenaz |
| ru-RU | Russian (Russian Federation) | Ацил КоА дегидрогеназа |
| fr-BE | French (Belgium) | Acyl-CoA déshydrogénase |
| fr-CA | French (Canada) | Acyl-CoA déshydrogénase |
| nl-NL | Dutch (Netherlands) | acyl-CoA-dehydrogenase |
| el-GR | Greek (Greece) | Ακυλο-CoA αφυδρογονάση Synonyms: Ακυλο-CoA αφυδρογονάση |
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