Version 2.77

Descriptions

An enzyme that catalyzes the hydrolysis of adenosine to inosine with the elimination of ammonia. Since there are wide tissue and species variations in the enzyme, it has been used as a tool in the study of human and animal genetics and in medical diagnosis. EC 3.5.4.4. Source: National Library of Medicine, MeSH 2006

Adenosine deaminase (ADA) is a purine salvage pathway enzyme, which catalyzes the irreversible deamination of adenosine into inosine and ammonia. Elevated adenosine deaminase activities are found in tuberculous pleural and pericardial effusions. In addition, increased ADA levels in cerebrospinal fluid (CSF) have been observed in tuberculous meningitis. These ADA increases are caused by the cellular immune response in the fluid compartment, especially in the activation of T lymphocytes. Thus, many disorders can cause elevations. Deficency of adenosine deaminase is the most frequent known cause of SCID (Severe combined immunodeficency disease) it is observed in 25% of cases. Source: Regenstrief Institute

Basic Part Properties

Part Display Name
Adenosine deaminase
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Adenosine deaminase

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15323-6

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 腺苷脱氨酶
Synonyms: ADA;腺甙脱氨酶
fr-CA French (Canada) Adénosine déaminase
et-EE Estonian (Estonia) Adenosiini deaminaas
es-ES Spanish (Spain) Adenosina deaminasa
it-IT Italian (Italy) Adenosina deaminasi
tr-TR Turkish (Turkey) Adenozin deaminaz
ru-RU Russian (Russian Federation) Аденозин деаминаза
Synonyms: Аденозиндезаминаза
nl-NL Dutch (Netherlands) adenosinedeaminase
fr-BE French (Belgium) Adénosine déaminase
Synonyms: ADA