LP15387-1
Angiotensin converting enzyme
Active
Descriptions
Angiotensin I converting enzyme (ACE, EC 3.4.15.1), an exopeptidase, is a circulating enzyme that participates in the body's renin-angiotensin system (RAS) which mediates extracellular volume (i.e. that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. It is secreted by pulmonary and renal endothelial cells and catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II. It is secreted by pulmonary and renal endothelial cells ACE degrades also bradykinin, a potent vasodilator, and other vasoactive peptides. These two actions make ACE inhibition a goal in the treatment of conditions such as high blood pressure, heart failure, diabetic nephropathy, and type 2 diabetes mellitus. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Angiotensin converting enzyme
Angiotensin converting enzyme (ACE) is an enzyme that assists in regulating blood pressure. ACE helps convert angiotensin I (inactive) to angiotensin II (active). Angiotensin II acts as a vasopressor and causes arteries to contract, increasing blood pressure. Medications called ACE inhibitors block the conversion of angiotensin I to angiotensin II in order to decrease blood pressure. The levels of ACE in the blood are also used in order to diagnose sarcoidosis. High levels of ACE in the blood could indicate early sarcoidosis and low levels of ACE in the blood could indicate chronic obstructive pulminary disease (COPD) or hypothyroidism. [Lab Tests Online:ace/tab/test] Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Angiotensin converting enzyme
- Part Display Name
- Angiotensin converting enzyme
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- ACE
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 血管紧张素转化酶 Synonyms: ACE; |
| es-ES | Spanish (Spain) | Enzima Convertidora de Angiotensina |
| el-GR | Greek (Greece) | Μετατρεπτικό ένζυμο της αγγειοτενσίνης Synonyms: Μετατρεπτικό ένζυμο της αγγειοτενσίνης |
| it-IT | Italian (Italy) | Angiotensina, enzima convertitore Synonyms: Enzima convertitore dell''angiotensina |
| et-EE | Estonian (Estonia) | Angiotensiini muundav ensüüm |
| tr-TR | Turkish (Turkey) | Anjiyotensin çevirici enzim |
| ru-RU | Russian (Russian Federation) | Ангиотензин превращающий фермент |
| fr-BE | French (Belgium) | Enzyme de conversion de l'angiotensine Synonyms: ACE |
| fr-CA | French (Canada) | Enzyme de conversion de l'angiotensine |
| nl-NL | Dutch (Netherlands) | angiotensine-converterend enzym |
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