LP15444-0
Bile acid
Active
Descriptions
Bile acids are steroid acids found predominantly in the bile of mammals. They are produced in the liver by the oxidation of cholesterol, and are stored in gallbladder and secreted into the intestine in the form of salts. They act as surfactants, emulsifying lipids and assisting with their absorption and digestion. Synthesis of bile acids is a major consumer of cholesterol. The body synthesizes about 800 mg of cholesterol per day and about half of that is used for bile acid synthesis. In total about 20-30 grams of bile acids are secreted into the intestine daily; about 90% of excreted bile acids are reabsorbed (by active transport in the ileum) and recycled. This is referred to as the enterohepatic circulation. Since bile acids are made from endogenous cholesterol, the enterohepatic circulation of bile acids may be disrupted as a way to lower cholesterol. This is the mechanism of action behind bile acid sequestrants. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Bile acid (Wikipedia)
The liver absorbs almost all bile except approximately 1% which spills to the peripheral circulation. With liver diseases, its ability to absorb bile acids may diminish, resulting in increased serum levels. Patients with intestinal malabsorption and metabolic disorders such as Gilbert's disease, Crigler-Najjar syndrome, or Dubin-Johnson syndrome do not exhibit elevated bile acids concentrations. Source: Regenstrief Institute
Basic Part Properties
- Part Display Name
- Bile acid
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Bile Ac
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 胆汁酸 Synonyms: BA; |
| fr-CA | French (Canada) | Acide biliaire |
| et-EE | Estonian (Estonia) | Sapphape |
| es-ES | Spanish (Spain) | Acido biliar |
| it-IT | Italian (Italy) | Acido biliare Synonyms: Acidi biliari |
| tr-TR | Turkish (Turkey) | Safra asidi |
| ru-RU | Russian (Russian Federation) | Желчная кислота Synonyms: Желчные кислоты |
| nl-NL | Dutch (Netherlands) | galzuur |
| fr-BE | French (Belgium) | Acide biliaire |
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