LP156721-5
HLA-DP+DQ+DR Ab.IgG
Active
Description
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- HLA-DP+DQ+DR IgG
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2012-07-03
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| pl-PL | Polish (Poland) | HLA-DP+DQ+DR Ab.IgG Synonyms: Przeciwciała IgG do HLA-DP, DQ i DR |
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