LP15695-7
Lecithin cholesterol acyltransferase
Active
Descriptions
Lecithin-cholesterol acyltransferase (LCAT, also called phosphatidylcholine-sterol O-acyltransferase) is an enzyme that converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol), which is then sequestered into the core of a lipoprotein particle, eventually making the newly synthesized HDL spherical and forcing the reaction to become unidirectional since the particles are removed from the surface. The enzyme is bound to high-density lipoproteins (HDLs) and low-density lipoproteins in the blood plasma. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia
Lecithin cholesterol acyltransferase deficiency (LCAT) deficiency is a disorder of lipoprotein metabolism. LCAT catalyzes the formation of cholesterol esters in lipoproteins. The disease has two forms: 1) familial LCAT deficiency in which there is complete LCAT deficiency and 2) fish eye disease in which there is a partial deficiency. Both are autosomal recessive disorders caused by mutations of the LCAT gene located on chromosome 16q22. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , LCAT deficiency
Basic Part Properties
- Part Name
- Lecithin cholesterol acyltransferase
- Part Display Name
- Lecithin cholesterol acyltransferase
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- LCAT
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 卵磷脂胆固醇酰基转移酶 Synonyms: LCAT; |
| es-ES | Spanish (Spain) | Lecitin colesterol aciltransferasa |
| it-IT | Italian (Italy) | Lecitina colesterolo aciltransferasi Synonyms: LCAT |
| tr-TR | Turkish (Turkey) | Lesitin kolesterol açiltransferaz |
| ru-RU | Russian (Russian Federation) | Лецитин холестерол ацилтрансфераза Synonyms: Лецитинхолестеринацилтрансфераза |
| fr-BE | French (Belgium) | Lécithine-cholestérol-acyltransférase |
| fr-CA | French (Canada) | Lécithine-cholestérol-acyltransférase |
| nl-NL | Dutch (Netherlands) | lecithinecholesterolacyltransferase |
| pl-PL | Polish (Poland) | Acylotransferaza lecytynowo-cholesterolowa Synonyms: Acylotransferaza lecytynowo-cholesterolowa |
| el-GR | Greek (Greece) | Λεκιθίνης χοληστερόλη ακυλοτρανσφεράση Synonyms: Λεκιθίνης χοληστερόλη ακυλοτρανσφεράση |
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