LP156998-9
ABCB1 gene.c.3435C>T
Active
Description
ABCB1 (also known as MDR1) is one of many ubiquitous adenosine triphosphate (ATP)-binding cassette (ABC) genes. ABCB1 encodes a transmembrane transporter, P-glycoprotein (P-gp), and plays a role in cell defense against environmental attacks. Many polymorphisms have been reported in this gene, including 1236C>T (rs1128503) in exon 12, 2677G>T (rs2032582) in exon 21 and 3435C>T (rs1045642) in exon 26. The 2677G>T variant is associated with a 2.6 fold higher risk of developing lung cancer. Individuals homozygous for the 2677G>T variant and heterozygous for the 3435C>T variant have up to a 20 fold higher risk of developing lung cancer. Source: Regenstrief LOINC, PMID: 17120199
Basic Part Properties
- Part Display Name
- ABCB1 gene c.3435C>T
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2012-07-17
- Construct for LOINC Short Name
- ABCB1 c.3435C>T
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP156998-9
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | ABCB1 基因.c.3435C>T |
| es-ES | Spanish (Spain) | Gen ABCB1 (MDR1) c.3435C>T |
| it-IT | Italian (Italy) | ABCB1 gene.c.3435C>T Synonyms: Gene ABCB1 c.3435C>T |
| tr-TR | Turkish (Turkey) | ABCB1 genie.c.3435C>T |
| ru-RU | Russian (Russian Federation) | ABCB1 ген.c.3435C>T |
| nl-NL | Dutch (Netherlands) | ABCB1-gen.c.3435C>T |
LOINC Copyright
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