LP15712-0
Lithocholate
Active
Description
Lithocholic acid (LCA) is the secondary bile acid (BA) formed from chenodeoxycholic acid (CDCA). Taurolithocholic acid (TLC) is also a secondary BA, which is formed from conjugation of LCA with taurine. BAs act as signaling molecules and affect macrophage cytokine expression. TLC is a strong agonist of TGR5, which is a G-protein coupled BA receptor expressed on macrophages. TLC modulates macrophages that are induced by lipopolysaccharide, which may contribute to the impaired response to bacterial and viral infections in patients with cholestasis. PMID: 29321478 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Lithocholate
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Lithocholate
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP15712-0 - ConceptMap translate
- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP15712-0
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 石胆酸 Synonyms: 石胆酸盐 |
| et-EE | Estonian (Estonia) | Litokolaat |
| es-ES | Spanish (Spain) | Litocolato |
| it-IT | Italian (Italy) | Litocolato |
| tr-TR | Turkish (Turkey) | Litokolat |
| ru-RU | Russian (Russian Federation) | Литохолат |
| nl-NL | Dutch (Netherlands) | lithocholaat |
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