LP157222-3
Centromere protein A
Active
Description
Centromere protein A (CENP-A) is an essential centromere protein encoded by the CENPA gene. Overexpression of CENP-A causes chromosomal aberrations, and depletion of CENP-A promotes apoptosis and induces cell cycle arrest. Overexpression of CENP-A has been associated with high grade cancers and is a prognostic factor for patients with estrogen receptor (ER)-positive breast cancer. Antibodies to CENP-A are associated with scleroderma, systemic sclerosis, CREST syndrome, and other rheumatologic diseases. Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Centromere protein A
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2012-08-22
- Construct for LOINC Short Name
- CENP A
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP157222-3
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 着丝粒蛋白 A Synonyms: 着丝点蛋白 A; |
| es-ES | Spanish (Spain) | Proteína A del centrómero (CENP-A) |
| it-IT | Italian (Italy) | Centromero, proteina A |
| tr-TR | Turkish (Turkey) | Sentromer protein A |
| ru-RU | Russian (Russian Federation) | Центромерный протеин A |
| nl-NL | Dutch (Netherlands) | centromeereiwit A |
LOINC Copyright
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