Version 2.77

Description

Centromere protein A (CENP-A) is an essential centromere protein encoded by the CENPA gene. Overexpression of CENP-A causes chromosomal aberrations, and depletion of CENP-A promotes apoptosis and induces cell cycle arrest. Overexpression of CENP-A has been associated with high grade cancers and is a prognostic factor for patients with estrogen receptor (ER)-positive breast cancer. Antibodies to CENP-A are associated with scleroderma, systemic sclerosis, CREST syndrome, and other rheumatologic diseases. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Centromere protein A
Part Type
Component (Describes the core component or analyte measured)
Created On
2012-08-22
Construct for LOINC Short Name
CENP A

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP157222-3

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 着丝粒蛋白 A
Synonyms: 着丝点蛋白 A;centromere protein A;CENP-A;CENPA
es-ES Spanish (Spain) Proteína A del centrómero (CENP-A)
it-IT Italian (Italy) Centromero, proteina A
tr-TR Turkish (Turkey) Sentromer protein A
ru-RU Russian (Russian Federation) Центромерный протеин A
nl-NL Dutch (Netherlands) centromeereiwit A