LP15729-4
Methemoglobin
Active
Descriptions
Methemoglobin is a form of the oxygen-carrying protein hemoglobin, in which the iron in the heme group is in the Fe3+ state, not the Fe2+ of normal hemoglobin. Metheomglobin appears blue and is unable to carry oxygen. The NADH-dependent enzyme methemoglobin reductase (AKA diaphorase I) is responsible for converting methemoglobin back to hemoglobin. Normally 1-2% of people's hemoglobin is methemoglobin, a higher percentage than this can be genetic or caused by exposure to various chemicals and depending on the level can cause health problems. A higher level of methemoglobin will tend to cause a pulse oximeter to read closer to 85% regardless of the true level of oxygen saturation. Methemoglobinemia can be caused by genetic abnormalities such as diaphorase I deficiency, or abnormal hemoglobin variants. It can also be caused by certain oxidizing drugs (benzocaine), antibiotics (trimethoprim or sulfanamides), analine dyes, metoclopramide, chlorates, bromates, and nitrates. Infants under 6 months are particularly susceptible when exposed to nitrates, benzocaine, or even dehydration. Methemoglobinemia can be treated with supplemental oxygen and methylene blue. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Methemoglobin (Wikipedia)
Brown pigment formed from hemoglobin by oxidation of the ferrous to the ferric state. Source: Regenstrief Institute
Basic Part Properties
- Part Display Name
- Methemoglobin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- MetHgb
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 高铁血红蛋白 Synonyms: Hi; |
| fr-CA | French (Canada) | Méthémoglobine |
| et-EE | Estonian (Estonia) | Methemoglobiin |
| es-ES | Spanish (Spain) | Metahemoglobina |
| it-IT | Italian (Italy) | Metaemoglobina Synonyms: Metemoglobina |
| tr-TR | Turkish (Turkey) | Methemoglobin |
| ru-RU | Russian (Russian Federation) | Метгемогломин |
| nl-NL | Dutch (Netherlands) | methemoglobine |
| fr-BE | French (Belgium) | Méthémoglobine |
| pl-PL | Polish (Poland) | Methemoglobina Synonyms: Methemoglobina |
LOINC Copyright
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