LP157421-1
TF gene
Active
Description
The TF gene (coagulation factor III (thromboplastin, tissue factor)) [HGNC Gene ID:11740] is located on chromosome 1p22-p21. This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] [NCBI Gene ID:2152] Source: National Center for Biotechnology Information (NCBI) Gene
Basic Part Properties
- Part Name
- TF gene
- Part Display Name
- TF gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2012-09-21
- Construct for LOINC Short Name
- TF gene
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP157421-1
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | TF 基因 Synonyms: Transferrin; |
| ru-RU | Russian (Russian Federation) | TF ген |
| es-ES | Spanish (Spain) | Gen TF |
| it-IT | Italian (Italy) | TF, gene Synonyms: Gene TF |
| tr-TR | Turkish (Turkey) | TF geni |
| nl-NL | Dutch (Netherlands) | TF-gen |
| el-GR | Greek (Greece) | Γονίδιο TF Synonyms: Γονίδιο TF |
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