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Description

A recurring chromosome aberration resulting in a dicentric chromosome, dic(9;20)(p11~13;q11), occurs in patients with acute lymphocytic leukemia (ALL), specifically B-cell precursor. Dic(9;20) occurs due to a breakpoint within the PAX5 gene on 9p, which fuses with one of a number of different genes on 20q. This usually results in loss of 9p and 20q material. It can occur as part of a complex karyotype or an individual cytogenetic abnormality. It is known to occur in the presence of the BCR-ABL1, t(9;22)(q34.1;q11), and ETV6-RUNX1, t(12;21)(p13;q22.3), fusion genes. Relapses after treatment are quite common. However, post-relapse treatment of many patients is successful. Source: Regenstrief LOINC

Reference Information

TypeSourceReference
CitationAtlas of Genetics and Cytogenetics in Oncology and HaematologyCopyright Copyright © Atlas of Genetics and Cytogenetics in Oncology and Haematology.Gibbons B . dic(9;20)(p11-13;q11). Atlas Genet Cytogenet Oncol Haematol. June 1999.Strefford JC . dic(9;20)(p11-13;q11). Atlas Genet Cytogenet Oncol Haematol. October 2009. URL: http://AtlasGeneticsOncology.org/Anomalies/dic920ID1143.html

Basic Part Properties

Part Name
dic(9;20)(p11-13;q11)(wcp9+,wcp20+)
Part Display Name
dic(9;20)(p11-13;q11)(wcp9+,wcp20+)
Part Type
Component (Describes the core component or analyte measured)
Created On
2012-09-28
Construct for LOINC Short Name
dic(9;20)(wcp9+,wcp20+)

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP157492-2

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)dic(9;20)(p11-13;q11)(wcp9+,wcp20+)
Synonyms: dicentric chromosome;双着丝粒染色体
es-ESSpanish (Spain)dic(9;20)(p11-13;q11)(wcp9+,wcp20+)
it-ITItalian (Italy)dic(9,20)(p11-13,q11)(wcp9+,wcp20+)
tr-TRTurkish (Turkey)dic(9;20)(p11-13;q11)(wcp9+,wcp20+)
ru-RURussian (Russian Federation)dic(9;20)(p11-13;q11)(wcp9+,wcp20+)
nl-NLDutch (Netherlands)dic(9;20)(p11-13;q11)(wcp9+,wcp20+)
fr-FRFrench (France)dic(9;20)(p11-13;q11)(wcp9+,wcp20+)
pl-PLPolish (Poland)Dic(9;20)(p11-13;q11)(wcp9+,wcp20+)
Synonyms: Dic(9;20)(p11-13;q11) z obecnym sygnałem sond centromerowych dla chromosomu 9 i 20
el-GRGreek (Greece)dic(9;20)(p11-13;q11)(wcp9+,wcp20+)
Synonyms: dic(9;20)(p11-13;q11)(wcp9+,wcp20+)