LP15824-3
Prostaglandin E2
Active
Description
Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin E2 is derived mainly from Prostaglandin H2, and is metabolized to Prostaglandin F2a, A2, and Dihydroketo Prostaglandin E2. Prostaglandin E2 is excreted directly into the urine. Prostaglandin E2 is a potent vasodilator and also a stimulus for Renin release. Prostaglandin E2 release is stimulated by cholinergic and alpha adrenergic agents. Prostaglandin E2 potentiates the actions of Histamine and Bradykinin causing pain and accumulation of edema fluid. It relaxes the circular muscle of the gut in opposition to Prostaglandin F2a, and also relaxes the lower esophageal sphincter. Prostaglandin E2 also causes accumulation of water and electrolytes in the lumen of the gut by stimulating their secretion. Elevated levels of Prostaglandin E2 have been detected in patients with the Watery Diarrhea Syndrome, neural crest tumors, pheochromocytomas, and other amine-peptide-secreting tumors. Prostaglandin E2 production and circulating levels are drastically suppressed by aspirin and indomethacin. Source: Inter Science Institute , Inter Science Institute
Basic Part Properties
- Part Name
- Prostaglandin E2
- Part Display Name
- Prostaglandin E2
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Prostaglandin E2
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 前列腺素 E2 Synonyms: PGE2 |
| es-ES | Spanish (Spain) | Prostaglandina E2 |
| it-IT | Italian (Italy) | Prostaglandina E2 |
| et-EE | Estonian (Estonia) | Prostaglandiin E2 |
| tr-TR | Turkish (Turkey) | Prostaglandin E2 |
| ru-RU | Russian (Russian Federation) | Простагландин E2 |
| fr-BE | French (Belgium) | Prostaglandine E2 Synonyms: PG E2 |
| fr-CA | French (Canada) | Prostaglandine E2 |
| nl-NL | Dutch (Netherlands) | prostagladine E2 |
| el-GR | Greek (Greece) | Προσταγλανδίνη E2 Synonyms: Προσταγλανδίνη E2 |
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