LP15905-0
Transcobalamin
Active
Description
Transcobalamins are carrier proteins which bind cobalamin (B12).
There are 2 types
1. Transcobalamin I (TCN1), also known as haptocorrin, R-factor, and R-protein, is a glycoprotein produced by the salivary glands of the mouth. It primarily serves to protect cobalamin (Vitamin B12) from acid degradation in the stomach by producing a Haptocorrin-Vitamin B12 complex. Once the complex has traveled to the more neutral duodenum, pancreatic proteases degrade haptocorrin, releasing free cobalamin, which now binds to intrinsic factor for absorption by ileal enterocytes.
2. Transcobalamin II (TCN2) binds cobalamin once it has been uptaken by enterocytes of the terminal ileum and the "Intrinsic Factor-Vitamin B12" complex has been degraded. The TCII-Vit B12 complex then enters portal circulation and is processed in the liver.
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Source: Wikipedia
, Wikipedia
Basic Part Properties
- Part Name
- Transcobalamin
- Part Display Name
- Transcobalamin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Transcobalamin
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP15905-0
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 运钴胺素蛋白 Synonyms: TC |
| es-ES | Spanish (Spain) | Transcobalamina |
| it-IT | Italian (Italy) | Transcobalamina Synonyms: TC |
| et-EE | Estonian (Estonia) | Transkobalamiin |
| tr-TR | Turkish (Turkey) | Transkobalamin |
| ru-RU | Russian (Russian Federation) | Транскобаламин |
| nl-NL | Dutch (Netherlands) | transcobalamine |
| el-GR | Greek (Greece) | Τρανσκοβαλαμίνη Synonyms: Τρανσκοβαλαμίνη |
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