Version 2.78

Descriptions

Sulbactam is a molecule which is given in combination with beta-lactam antibiotics to overcome beta-lactamase, an enzyme produced by bacteria that destroys the antibiotics. Sulbactam is an irreversible inhibitor of beta-lactamase; it binds the enzyme and does not allow it to interact with the antibiotic. Sulbactam is able to inhibit the most common forms of beta-lactamase but is not able to interact with the ampC cephalosporinase. Thus, it confers little protection against bacteria such as Pseudomonas aeruginosa , Citrobacter , Enterobacter , and Serratia , which often express this gene. In the United States, sulbactam is combined to form cefoperazonesulbactam and ampicillinsulbactam. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Sulbactam (Wikipedia)

A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone. Source: National Library of Medicine, MeSH 2006

Basic Part Properties

Part Display Name
Sulbactam
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Sulbactam

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15938-1
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP15938-1

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 舒巴坦
Synonyms: 舒巴坦酸;舒巴克坦;舒巴坦;青霉砜;青霉烷砜;青霉烷砜酸;SALBACTAM ACID;(2S-cis)-3,3-dimethyl-7-oxy-4-sulph-1-aza dicyclo[3,2,0]heptane-2-carboxylic acid 4,4-dioxide;(2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide;penicillanic acid sulfone
fr-CA French (Canada) Sulbactame
et-EE Estonian (Estonia) Sulbaktaam
es-ES Spanish (Spain) Sulbactam
it-IT Italian (Italy) Sulbactam
tr-TR Turkish (Turkey) Sulbaktam
ru-RU Russian (Russian Federation) Сульбактам
nl-NL Dutch (Netherlands) sulbactam
fr-BE French (Belgium) Sulbactame