LP16048-8
Cocaine
Active
Descriptions
Cocaine is an alkaloid of Erythroxylon coca that is grown in the northern South American Andes, India, Africa and Java. It is used medicinally as a local anesthetic and vasoconstrictor in nasal surgery and to dilate pupils. Because cocaine is a powerful central nervous system stimulant it is among the most abused drugs. Cocaine abuse can lead to sudden death due to cardiotoxicity or the sequential development of hyperthermia, agitated delirium and respiratory arrest. Cocaine is metabolized in the liver to inactive benzoylecgonine (BZE). BZE is pharmacologically inactive and has a longer half-life than its parent drug cocaine. It is the substance most tested for when investigating suspected cocaine abuse. Cocaethylene (CE) is produced in the liver in the presence of ethanol and has been shown to have similar stimulatory effects as cocaine in animal studies.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition) Cocaethylene is toxic to the myocardium. PMID: 8761012 Source: Regenstrief LOINC
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake. Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Display Name
- Cocaine
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Cocaine
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP16048-8 - ConceptMap translate
- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP16048-8
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 可卡因 Synonyms: C17H21NO4; |
| fr-CA | French (Canada) | Cocaïne |
| et-EE | Estonian (Estonia) | Kokaiin |
| es-ES | Spanish (Spain) | Cocaína |
| it-IT | Italian (Italy) | Cocaina |
| tr-TR | Turkish (Turkey) | Kokain |
| ru-RU | Russian (Russian Federation) | Кокаин |
| nl-NL | Dutch (Netherlands) | cocaïne |
| fr-BE | French (Belgium) | Cocaïne |
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright