LP16156-9
Norfloxacin
Active
Descriptions
Norfloxacin is an oral broad-spectrum quinolone antibacterial agent used in the treatment of urinary tract infections. Action::The mechanism of action of norfloxacin involves inhibition of the A subunit of bacterial DNA gyrase, an enzyme which is essential for DNA replication. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Norfloxacin (Wikipedia)
A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE. Source: National Library of Medicine, MeSH 2006
Book Reference
Norfloxacin is a synthetic broad-spectrum fluorquinolone that is effective against aerobic and anaerobic Gram-positive and Gram-negative bacteria. Norfloxacin blocks bacterial enzyme activity of DNA gyrase and topoisomerase that are required to synthesize mRNA and DNA for bacterial replication. Norfloxacin was used for years to treat many bacterial infections, but now has limited indications for urinary tract infections, prostatitis, and sexually transmitted diseases caused by sensitive organisms. Side effects of norfloxacin include gastrointestinal upset, skin rash, and allergic reactions. More severe reactions to treatment using norfloxacin included prolongation of the QT interval, seizures, hallucinations, tendon rupture, hypersensitivity reactions, angioedema, photosensitivity and peripheral neuropathy. It has rarely been associated with acute hepatocellular injury.[https://www.ncbi.nlm.nih.gov/books/NBK547850/]
Basic Part Properties
- Part Name
- Norfloxacin
- Part Display Name
- Norfloxacin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Norfloxacin
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 诺氟沙星 Synonyms: 氟哌酸 |
| es-ES | Spanish (Spain) | Norfloxacina |
| it-IT | Italian (Italy) | Norfloxacina |
| et-EE | Estonian (Estonia) | Norfloksatsiin |
| tr-TR | Turkish (Turkey) | Norflokzasin |
| ru-RU | Russian (Russian Federation) | Норфлоксацин |
| fr-BE | French (Belgium) | Norfloxacine |
| fr-CA | French (Canada) | Norfloxacine |
| nl-NL | Dutch (Netherlands) | norfloxacine |
| el-GR | Greek (Greece) | Νορφλοξασίνη Synonyms: Νορφλοξασίνη |
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