LP16353-2
Complement C1r
Active
Description
A 80-kDa subcomponent of complement C1, existing as a SERINE PROTEASE proenzyme in the intact complement C1 complex. When COMPLEMENT C1Q is bound to antibodies, the changed tertiary structure causes autolytic activation of complement C1r which is cleaved into two chains, A (heavy) and B (light, the serine protease), connected by disulfide bonds. The activated C1r serine protease, in turn, activates COMPLEMENT C1S proenzyme by cleaving the Arg426-Ile427 bond. No fragment is released when either C1r or C1s is cleaved. Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Name
- Complement C1r
- Part Display Name
- Complement C1r
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- C1r
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 补体 C1r |
| es-ES | Spanish (Spain) | Factor C1r del complemento |
| it-IT | Italian (Italy) | Complemento C1r |
| et-EE | Estonian (Estonia) | Komplemendi komponent C1r |
| tr-TR | Turkish (Turkey) | Kompleman C1r |
| ru-RU | Russian (Russian Federation) | Комплемент C1r |
| fr-BE | French (Belgium) | Complément C1r |
| fr-CA | French (Canada) | Complément C1r |
| nl-NL | Dutch (Netherlands) | complement C1r |
| el-GR | Greek (Greece) | Συμπλήρωμα C1r Synonyms: Συμπλήρωμα C1r |
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