LP16357-3
Complement C1s
Active
Description
A 77-kDa subcomponent of complement C1, encoded by gene C1S, is a SERINE PROTEASE existing as a proenzyme (homodimer) in the intact complement C1 complex. Upon the binding of COMPLEMENT C1Q to antibodies, the activated COMPLEMENT C1R cleaves C1s into two chains, A (heavy) and B (light, the serine protease), linked by disulfide bonds yielding the active C1s. The activated C1s, in turn, cleaves COMPLEMENT C2 and COMPLEMENT C4 to form C4b2a (CLASSICAL C3 CONVERTASE). Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Name
- Complement C1s
- Part Display Name
- Complement C1s
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- C1s
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 补体 C1s |
| fr-CA | French (Canada) | Complément C1s |
| et-EE | Estonian (Estonia) | Komplemendi komponent C1s |
| es-ES | Spanish (Spain) | Factor C1s del complemento |
| it-IT | Italian (Italy) | Complemento C1s |
| tr-TR | Turkish (Turkey) | Kompleman C1s |
| ru-RU | Russian (Russian Federation) | Комплемент C1s |
| nl-NL | Dutch (Netherlands) | complement C1s |
| fr-BE | French (Belgium) | Complément C1s |
| fr-FR | French (France) | Complément C1s |
| pl-PL | Polish (Poland) | Dopełniacz C1s Synonyms: Składowa C1s dopełniacza |
| el-GR | Greek (Greece) | Συμπλήρωμα C1s Synonyms: Συμπλήρωμα C1s |
LOINC Copyright
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