LP16365-6
Complement C3d
Active
Descriptions
A 302-amino-acid fragment in the alpha chain (672-1663) of C3b. It is generated when C3b is inactivated (iC3b) and its alpha chain is cleaved by COMPLEMENT FACTOR I into C3c, and C3dg (955-1303) in the presence COMPLEMENT FACTOR H. Serum proteases further degrade C3dg into C3d (1002-1303) and C3g (955-1001). Source: National Library of Medicine, MeSH 2006
Complement C3d developed for the detection of Circulating Immune Complexes (CICs). Other CICs tests include PEG precipitation, radial immunodiffusion and cellular based assays, such as the Raji cell assay. No single procedure appears to detect all types of CIC; however, those procedures that detect CICs containing fragments of complement (e.g., C1q and C3d) appear to detect clinically relevant events. C3d is a fragment of the ProC3 cleaved protein once activation begins. C3d is associated with Antibody;Antigen complexes during active phases of disease by the end result of a series of cleavage products. (Test information from Quest Diagnostics). Source: Regenstrief Institute
Basic Part Properties
- Part Name
- Complement C3d
- Part Display Name
- Complement C3d
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- C3d
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 补体 C3d |
| es-ES | Spanish (Spain) | Factor C3d del complemento |
| it-IT | Italian (Italy) | Complemento C3d |
| et-EE | Estonian (Estonia) | Komplemendi komponent C3d |
| tr-TR | Turkish (Turkey) | Kompleman C3d |
| ru-RU | Russian (Russian Federation) | Комплемент C3d |
| fr-BE | French (Belgium) | Complément C3d |
| fr-CA | French (Canada) | Complément C3d |
| nl-NL | Dutch (Netherlands) | complement C3d |
| el-GR | Greek (Greece) | Συμπλήρωμα C3d Synonyms: Συμπλήρωμα C3d |
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