Version 2.78

Description

AChR antibodies and striated muscle antibodies have been detected in patients with Myasthenia gravis (MG), thymoma without neurological symptoms, and in patients with other autoimmune diseases, including, for example, Lambert-Eaton disease, myasthenic syndrome, rheumatoid arthritis, systemic lupus erythematosus, Graves disease, and autoimmune liver disease.

AChR antibodies are further characterized into three categories; binding, blocking, and modulating.
ACHR-binding antibodies are detected in 90% of patients with severe, generalized MG, and 50% of patients with ocular MG. ACHR-modulating antibodies and ACHR-blocking antibodies are detected in approximately 65% to 70% of MG patients. Source: ARUP Laboratories

Basic Part Properties

Part Display Name
Acetylcholine receptor blocking
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
AChR Block

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP16663-4

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 乙酰胆碱受体封闭
Synonyms: AChR 封闭;乙酰胆碱受体封闭（Acetylcholine Receptor Antibodies，ACRA）
fr-CA French (Canada) Blocage du récepteur de l'acétylcholine
es-ES Spanish (Spain) Bloqueador del receptor de acetilcolina
it-IT Italian (Italy) Acetilcolina, recettore bloccante
Synonyms: Recettore bloccante l''acetilcolina
tr-TR Turkish (Turkey) Asetilkolin reseptörü kapatıcı
ru-RU Russian (Russian Federation) Ацетилхолин рецептор блокирующий
Synonyms: Ацетилхолинового рецептора блокирующий
nl-NL Dutch (Netherlands) acetylcholinereceptorblokkade
fr-BE French (Belgium) Blocage du récepteur de l'acétylcholine